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U.S. ICD-10-CM · April 2026

D89 ICD-10-CM Code: Other disorders involving the immune mechanism, not elsewhere classified

A clear reference for the official code description, hierarchy, and related coding information from the April 2026 U.S. release.

Code definition

Official description

D89

Other disorders involving the immune mechanism, not elsewhere classified

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where D89 sits

  1. 1

    Chapter 3

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

  2. 2

    Section

    Certain disorders involving the immune mechanism (D80-D89)

  3. 3

    Category D89

    Other disorders involving the immune mechanism, not elsewhere classified

  4. 4

    Code D89

    Other disorders involving the immune mechanism, not elsewhere classified

More specific choices

Codes under D89

D89 is a non-billable category. Choose the child code that best matches the documented diagnosis.

D89.0

Polyclonal hypergammaglobulinemia

D89.1

Cryoglobulinemia

D89.2

Hypergammaglobulinemia, unspecified

D89.3

Immune reconstitution syndrome

D89.4

Mast cell activation syndrome and related disorders

D89.8

Other specified disorders involving the immune mechanism, not elsewhere classified

D89.9

Disorder involving the immune mechanism, unspecified

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for D89.

Code first

No “code first” instruction is listed for D89.

Use additional code

No “use additional code” instruction is listed for D89.

Excludes1

Conditions that should not be reported together with this code.

  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2

Conditions not included here that may be reported separately when present.

  • transplant failure and rejection (T86.-)

Transparency

Source and release

Data release

U.S. ICD-10-CM · April 2026

Effective date

Apr 1, 2026

Publisher

Vero Scribe Inc.

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code D89 mean?

D89 is the April 2026 U.S. ICD-10-CM code for “Other disorders involving the immune mechanism, not elsewhere classified.”

Is D89 a billable or specific ICD-10-CM code?

No. D89 has more specific child codes in the April 2026 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is D89 located in ICD-10-CM?

D89 is listed in Chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), within Certain disorders involving the immune mechanism (D80-D89) (D80–D89), under category D89, Other disorders involving the immune mechanism, not elsewhere classified.

What coding notes are listed for D89?

No inclusion terms are listed for D89 in this reference record. No code-first instruction is listed. Excludes1 notes: hyperglobulinemia NOS (R77.1); monoclonal gammopathy (of undetermined significance) (D47.2). Excludes2 notes: transplant failure and rejection (T86.-).

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