U.S. ICD-10-CM · FY 2027

D57 ICD-10-CM Code: Sickle-cell disorders

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

D57

Sickle-cell disorders

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where D57 sits

  1. 1

    Chapter 3

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

  2. 2

    Section

    Hemolytic anemias (D55-D59)

  3. 3

    Category D57

    Sickle-cell disorders

  4. 4

    Code D57

    Sickle-cell disorders

More specific choices

Codes under D57

D57 is a non-billable category. Choose the child code that best matches the documented diagnosis.

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for D57.

Code first

No “code first” instruction is listed for D57.

Use additional code

  • code for any associated fever (R50.81)

Excludes1

Conditions that should not be reported together with this code.

  • other hemoglobinopathies (D58.-)

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for D57.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code D57 mean?

D57 is the FY 2027 U.S. ICD-10-CM code for “Sickle-cell disorders.”

Is D57 a billable or specific ICD-10-CM code?

No. D57 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is D57 located in ICD-10-CM?

D57 is listed in Chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), within Hemolytic anemias (D55-D59) (D55–D59), under category D57, Sickle-cell disorders.

What coding notes are listed for D57?

No inclusion terms are listed for D57 in this reference record. No code-first instruction is listed. Additional-code instructions: code for any associated fever (R50.81). Excludes1 notes: other hemoglobinopathies (D58.-). No Excludes2 note is listed.

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