U.S. ICD-10-CM · FY 2027

D57.458 ICD-10-CM Code: Sickle-cell thalassemia beta plus with crisis with other specified complication

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

D57.458

Sickle-cell thalassemia beta plus with crisis with other specified complication

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where D57.458 sits

  1. 1

    Chapter 3

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

  2. 2

    Section

    Hemolytic anemias (D55-D59)

  3. 3

    Category D57

    Sickle-cell disorders

  4. 4

    Subcategory D57.45

    Sickle-cell thalassemia beta plus with crisis

  5. 5

    Code D57.458

    Sickle-cell thalassemia beta plus with crisis with other specified complication

Documentation details

Notes for this code

Inclusion terms

  • HbS-beta plus with crisis with other specified complication
  • Sickle-cell beta plus with crisis with other specified complication

Code first

No “code first” instruction is listed for D57.458.

Use additional code

  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for D57.458.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for D57.458.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

Publisher

Vero Scribe Inc.

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code D57.458 mean?

D57.458 is the FY 2027 U.S. ICD-10-CM code for “Sickle-cell thalassemia beta plus with crisis with other specified complication.”

Is D57.458 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, D57.458 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is D57.458 located in ICD-10-CM?

D57.458 is listed in Chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), within Hemolytic anemias (D55-D59) (D55–D59), under category D57, Sickle-cell disorders and subcategory D57.45, Sickle-cell thalassemia beta plus with crisis.

What coding notes are listed for D57.458?

Its listed inclusion terms are HbS-beta plus with crisis with other specified complication; Sickle-cell beta plus with crisis with other specified complication. No code-first instruction is listed. Additional-code instructions: code to identify complications, such as:; cholelithiasis (K80.-); priapism (N48.32). No Excludes1 note is listed. No Excludes2 note is listed.

Keep exploring

Related D57.45 codes

D57.451

Sickle-cell thalassemia beta plus with acute chest syndrome

D57.452

Sickle-cell thalassemia beta plus with splenic sequestration

D57.453

Sickle-cell thalassemia beta plus with cerebral vascular involvement

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