D57.453 ICD-10-CM Code: Sickle-cell thalassemia beta plus with cerebral vascular involvement
A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.
Code definition
Official description
D57.453Sickle-cell thalassemia beta plus with cerebral vascular involvement
ICD-10-CM diagnosis code · United States clinical modification
Classification
Where D57.453 sits
- 1
Chapter 3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- 2
Section
Hemolytic anemias (D55-D59)
- 3
Category D57
Sickle-cell disorders
- 4
Subcategory D57.45
Sickle-cell thalassemia beta plus with crisis
- 5
Code D57.453
Sickle-cell thalassemia beta plus with cerebral vascular involvement
Documentation details
Notes for this code
Inclusion terms
- HbS-beta plus with cerebral vascular involvement
- Sickle-cell beta plus with cerebral vascular involvement
Code first
No “code first” instruction is listed for D57.453.
Use additional code
No “use additional code” instruction is listed for D57.453.
Excludes1
Conditions that should not be reported together with this code.
No Excludes1 note is listed for D57.453.
Excludes2
Conditions not included here that may be reported separately when present.
No Excludes2 note is listed for D57.453.
Transparency
Source and release
This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.
Review the CDC/NCHS ICD-10-CM sourceCode-specific guidance
Frequently asked questions
What does ICD-10-CM code D57.453 mean?
D57.453 is the FY 2027 U.S. ICD-10-CM code for “Sickle-cell thalassemia beta plus with cerebral vascular involvement.”
Is D57.453 a billable or specific ICD-10-CM code?
Yes. In the FY 2027 reference data used on this page, D57.453 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.
Where is D57.453 located in ICD-10-CM?
D57.453 is listed in Chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), within Hemolytic anemias (D55-D59) (D55–D59), under category D57, Sickle-cell disorders and subcategory D57.45, Sickle-cell thalassemia beta plus with crisis.
What coding notes are listed for D57.453?
Its listed inclusion terms are HbS-beta plus with cerebral vascular involvement; Sickle-cell beta plus with cerebral vascular involvement. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.
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