Mood Disorder Questionnaire (MDQ)

The MDQ is a self-report screen for bipolar disorder. It asks whether there has ever been a period of manic or hypomanic symptoms, whether they came together, and how much trouble they caused. See the three-part rule for a positive screen, what to do with each result, and how to record it with the free template. The official form is linked from this page.

  • Score bands explained
  • Recording template to copy
  • Two recorded examples

MDQ result template

Free
MOOD DISORDER QUESTIONNAIRE

Date: [Date completed]
Patient: [Name or record number, age]
Form: [Paper, tablet, or portal; language; read aloud or help given]
Reason for screening: [Depression before an antidepressant, poor response to treatment, intake, or other]

PART 1 TO PART 3
Part 1 yes count: [Number out of 13; any items left blank]
Part 2, same period: [Yes, no, or not answered]
Part 3, how much of a problem: [No, minor, moderate, or serious problem]
Family history and past diagnosis: [Answers to the two unscored questions, if on the form used]

SCREEN RESULT
Result: [Positive, negative, or incomplete until a blank part is answered]
Rule used: [Standard rule of 7 or more yes, same period, moderate or serious problem; or the modified rule your service uses]

HISTORY TAKEN TODAY
Periods described: [When, how long, sleep, energy, spending, risks taken, who noticed]
Current mood: [Depressed, elevated, mixed, or level, with PHQ-9 or other scores]
Other explanations: [Substances, stimulants or steroids, thyroid disease, ADHD, borderline personality, trauma]
Collateral: [Partner or family account with consent, or not yet obtained]
Impression: [Screen result in words, or working diagnosis]

DECISION
Next step: [Psychiatric assessment, referral, or watch and review]
Medication: [Antidepressant held or started, mood stabilizer, or no change, with the reason]
Safety: [Suicidal thoughts asked about directly, and the answer]
Follow-up: [Who arranges it and by when]

Screened by: [Name, credentials]

Get the official MDQ from its source.

Who holds it

Robert M. A. Hirschfeld, MD, and colleagues, from their 2000 paper in the American Journal of Psychiatry. The form carries a 2000 copyright notice from The University of Texas Medical Branch.

How you may use it

The MDQ is copyrighted. The copy shared by the University of Washington’s Psychiatry Consultation Line notes that Dr. Hirschfeld granted permission for its use, and Mental Health America says use needs the author’s permission. Ask before you reprint it, put it online, or build it into software; this page doesn’t reproduce the questions.

Use it for

  • Before starting an antidepressant
  • Depression that won’t lift
  • Psychiatry intake
  • Primary care mental health
  • Collaborative care

What the score means. 0 to 13, part 1 items answered yes.

0 to 6: Below the item threshold

A negative screen, whatever parts 2 and 3 say. It doesn’t rule out bipolar disorder: when the history points to past highs, assess anyway.

7 to 13: Meets the item threshold

Positive only when part 2 is yes and part 3 is a moderate or serious problem. A positive screen calls for a diagnostic assessment before decisions such as starting an antidepressant alone.
  • Count the yes answers in part 1, from 0 to 13. Parts 2 and 3 aren’t added to the count; they decide whether a count of 7 or more is a positive screen.
  • The standard positive screen needs all three: 7 or more yes answers in part 1, yes to part 2 (several of the symptoms happened in the same period), and a moderate or serious problem in part 3.
  • Many copies of the form add two unscored questions, on bipolar disorder in blood relatives and on any past diagnosis. Record the answers; they feed the assessment.
  • Part 1 asks about any period in the person’s life, not the last two weeks. A positive screen points to past mania or hypomania, not to the mood the person is in today.
  • In the original 2000 study of 198 outpatients at mood disorder clinics, the rule found bipolar disorder with 73% sensitivity and 90% specificity. In a general population study sensitivity was 28% with 97% specificity, and in primary care patients treated for depression, 58% and 93%.
  • A 2015 meta-analysis put sensitivity at 62% and specificity at 85% with the cutoff of 7. In studies that left out people already known to have bipolar disorder, sensitivity fell to 37%.
  • It finds bipolar I better than bipolar II. In a 2004 clinic study it picked up under a third of people with bipolar II or bipolar disorder not otherwise specified, often because hypomania didn’t feel like a moderate or serious problem to them.
  • Some studies and services drop the part 2 and part 3 requirements, or lower the item count, to catch more bipolar II. That finds more people but flags more who don’t have bipolar disorder. The standard rule is all three parts; name any other rule you use.
  • It screens; it doesn’t diagnose. A positive result leads to a diagnostic interview, and a negative one doesn’t close the question when the history is suggestive.

How to give it, score it, and read it.

When to use it

Give it to people with depression, now or in the past, before you decide on treatment. It matters most when an antidepressant is on the table.

  • Adults with a current or past episode of depression
  • Before starting or switching an antidepressant
  • Depression that keeps coming back, began young, or hasn’t lifted on two treatments
  • A family history of bipolar disorder, or a past high after an antidepressant

Avoid: Using it as a population screen in people with no mood symptoms. In a general population study it found only 28% of people with bipolar disorder.

Giving it

The patient completes it alone, on paper or a screen, in about 5 minutes. Hand it over before the visit, so the conversation doesn’t shape the answers.

  • Explain that the questions cover any time in their life, not only now
  • Use a validated translation where one exists, and note the language used
  • Check that parts 2 and 3 are answered before the patient leaves
  • Add a partner’s or family member’s account, with consent: people often don’t recall or recognize their own highs

Avoid: Letting the patient read part 1 as “in the last two weeks”. A depressed patient will answer no to almost everything.

Scoring

Count the yes answers in part 1, then check parts 2 and 3. A positive screen needs all three.

  • Part 1: 7 or more of the 13 items answered yes
  • Part 2: yes, several of the symptoms happened in the same period
  • Part 3: a moderate or serious problem, such as trouble at work, with money, or in relationships
  • A blank part makes the screen incomplete; ask the question rather than scoring it as no

Avoid: Calling a count of 7 or more positive on its own. A count of 10 with no to part 2 is a negative screen on the standard rule.

Reading the result

A positive screen means bipolar disorder is possible and needs a diagnostic assessment. A negative screen lowers the chance but doesn’t rule it out.

  • Take a history of each period: when, how long, sleep, energy, behavior, and whether others noticed
  • Check the length: a manic episode lasts at least a week or needs hospital care; hypomania lasts at least 4 days in a row
  • Look for other causes of the highs: stimulants, steroids, alcohol or drugs, thyroid disease
  • Consider conditions that raise the count: ADHD, borderline personality disorder, anxiety, and substance use

Avoid: Diagnosing bipolar disorder from a positive screen. Even in the original clinic study, 1 in 10 people without it screened positive.

Before an antidepressant

In bipolar depression an antidepressant on its own can bring on mania or a mixed state, so a positive screen changes the next step.

  • Hold off on an antidepressant alone until a positive screen has been assessed
  • Ask about highs after past antidepressants, bipolar disorder in the family, and early or frequent episodes
  • Ask directly about suicidal thoughts: they’re common in bipolar depression and mixed states
  • Record the decision and the reason, so the next clinician sees why treatment waited

Avoid: Waiting on a routine referral when there is current suicide risk or severe depression. Act on the risk now.

Two recorded results. Every part, filled in.

Each one follows the recording template. Use them to judge how much to write.

MDQ result: positive screen before an antidepressant

Primary care clinic, return visit for a third episode of depression, paper form before the appointment

Part 1 to part 3

Part 1: 9 of 13 yes, every item answered. Part 2: yes. Part 3: serious problem. Family history: her mother has bipolar I disorder. Past diagnosis: none.

Screen result

Positive on the standard rule: 9 yes, together in the same period, and a serious problem.

History taken today

27-year-old woman, a graphic designer, in her third episode of depression since age 19. PHQ-9 today 18. She describes two spells, in 2023 and last spring, each about a week long: 3 to 4 hours of sleep a night without feeling tired, racing thoughts, and several new projects at once. She walked out of a job during the second. Her partner, at the visit with her consent, remembers both. No stimulants or cannabis, 2 drinks a week, TSH normal in August. Impression: possible bipolar disorder, not yet diagnosed.

Decision

No antidepressant started today; she agreed once we talked through the risk of bringing on a high. Psychiatry assessment booked for November 24. Asked directly about suicidal thoughts: none; 988 given for a crisis. The practice nurse calls her weekly until the assessment, and she comes in sooner if her sleep drops again.

Common mistakes, and how to avoid them.

Scoring from the count alone

Seven or more yes answers is only the first of three conditions. Check the same-period answer and the problem rating before calling it positive.

Treating a negative as a rule-out

The MDQ misses many people with bipolar II, whose highs often don’t feel like a problem. When the history points to past highs, assess anyway.

Reading it as today’s mood

The questions cover the whole lifetime. A positive screen in a depressed patient points to past highs, not current mania.

Calling a positive screen bipolar disorder

ADHD, borderline personality disorder, substance use, and anxiety all raise the count. The diagnosis comes from a full history, ideally with someone who knows the patient well.

Say the three parts. Review the note.

Vero Scribe records the MDQ result in your template from the visit, with the patient’s consent, or from your dictation: the yes count, parts 2 and 3, the result, the history you took, and the decision. You review and edit every line, then copy it into your record. Vero works in 60+ languages.

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Frequently asked questions.

How do you score the MDQ?

Count the yes answers in part 1, from 0 to 13. The screen is positive when there are 7 or more yes answers, part 2 is yes, meaning several of the symptoms happened in the same period, and part 3 is a moderate or serious problem. All three are needed. The background questions on family history and past diagnosis aren’t scored.

What does a positive MDQ mean?

That bipolar disorder is possible and needs a diagnostic assessment. It isn’t a diagnosis: in the original clinic study, about 1 in 10 people without bipolar disorder still screened positive, and ADHD, borderline personality disorder, and substance use can all raise the count.

What is the MDQ cutoff?

7 or more yes answers out of 13, together with yes to part 2 and a moderate or serious problem in part 3. Some studies drop parts 2 and 3 or use a lower count to find more bipolar II, which finds more people and flags more who don’t have it. Record which rule you used.

Does the MDQ detect bipolar II?

Less well than bipolar I. Hypomania often doesn’t feel like a problem, so part 3 is answered no or minor problem and the screen comes out negative. In one clinic study it picked up under a third of people with bipolar II or related forms. When the history suggests past highs, assess anyway.

How is the MDQ different from the YMRS?

The MDQ is a self-report screen for a lifetime history of mania or hypomania. The YMRS is rated by a clinician from an interview and measures how severe mania is now, in someone already assessed, on a scale of 0 to 60. One asks whether it ever happened; the other asks how bad it is today.

Should the MDQ be given with the PHQ-9?

Often, yes. The PHQ-9 measures current depression but can’t tell depression in bipolar disorder from unipolar depression. Adding the MDQ when depression is found, especially before an antidepressant, checks for past highs.

Show all questions
What other bipolar screening questionnaires are there?

The HCL-32, a 32-item hypomania checklist, was better than the MDQ at finding bipolar II in mental health settings in a 2015 meta-analysis. The Bipolar Spectrum Diagnostic Scale is another self-report option. Whichever you use, a positive result leads to the same diagnostic assessment.

Is there an MDQ for teenagers?

Yes. The MDQ-A, published in 2006, has a parent answer about their teenager. In an adolescent psychiatry clinic, the parent version with 5 or more yes answers found 72% of teens with bipolar disorder, with 81% specificity; the teens’ own answers did less well.

Is the MDQ free, and where do I get the form?

It’s widely used in clinics, but it’s copyrighted. A copy with the scoring rule, shared with Dr. Hirschfeld’s permission, is on the University of Washington Psychiatry Consultation Line’s site, linked from this page; ask the author before you reprint it or build it into software. Anyone on the care team can hand it out, and a clinician reads the result. The recording template on this page is free to copy or download.

More mental health tools, and templates.

PHQ-9

Nine questions on the last two weeks: depression screening and severity, scored 0 to 27.

Open the PHQ-9

PHQ-2

Two questions on interest and mood: a quick first screen for depression, scored 0 to 6.

Open the PHQ-2

GAD-7

Seven questions on worry and tension: anxiety screening and severity, scored 0 to 21.

Open the GAD-7

C-SSRS

Up to six questions on suicidal thoughts and behavior; the highest yes sets low, moderate, or high risk.

Open the C-SSRS

PCL-5

Twenty items on the past month: PTSD screening and symptom tracking, scored 0 to 80.

Open the PCL-5

MDQ PDF and screening documentation

Where to find the form, what each validation study measured, and how to correct a mis-scored or incomplete record.

Learn more about MDQ PDF and screening documentation

Psychiatric evaluation template

The full assessment a positive screen leads to: episode history, mental status, risk, and diagnosis.

Learn more about Psychiatric evaluation template

Young Mania Rating Scale

How severe mania is now, once bipolar disorder is known: 11 items, scored 0 to 60.

Learn more about Young Mania Rating Scale

All screening tools

Every tool, by area, with what its scores mean.

Learn more about All screening tools

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