U.S. ICD-10-CM · FY 2027

D80 ICD-10-CM Code: Immunodeficiency with predominantly antibody defects

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

D80

Immunodeficiency with predominantly antibody defects

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where D80 sits

  1. 1

    Chapter 3

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

  2. 2

    Section

    Certain disorders involving the immune mechanism (D80-D89)

  3. 3

    Category D80

    Immunodeficiency with predominantly antibody defects

  4. 4

    Code D80

    Immunodeficiency with predominantly antibody defects

More specific choices

Codes under D80

D80 is a non-billable category. Choose the child code that best matches the documented diagnosis.

D80.0

Hereditary hypogammaglobulinemia

D80.1

Nonfamilial hypogammaglobulinemia

D80.2

Selective deficiency of immunoglobulin A [IgA]

D80.3

Selective deficiency of immunoglobulin G [IgG] subclasses

D80.4

Selective deficiency of immunoglobulin M [IgM]

D80.5

Immunodeficiency with increased immunoglobulin M [IgM]

D80.6

Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia

D80.7

Transient hypogammaglobulinemia of infancy

D80.8

Other immunodeficiencies with predominantly antibody defects

D80.9

Immunodeficiency with predominantly antibody defects, unspecified

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for D80.

Code first

No “code first” instruction is listed for D80.

Use additional code

No “use additional code” instruction is listed for D80.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for D80.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for D80.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

Publisher

Vero Scribe Inc.

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code D80 mean?

D80 is the FY 2027 U.S. ICD-10-CM code for “Immunodeficiency with predominantly antibody defects.”

Is D80 a billable or specific ICD-10-CM code?

No. D80 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is D80 located in ICD-10-CM?

D80 is listed in Chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), within Certain disorders involving the immune mechanism (D80-D89) (D80–D89), under category D80, Immunodeficiency with predominantly antibody defects.

What coding notes are listed for D80?

No inclusion terms are listed for D80 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.

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