U.S. ICD-10-CM · FY 2027

E88 ICD-10-CM Code: Other and unspecified metabolic disorders

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

E88

Other and unspecified metabolic disorders

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where E88 sits

  1. 1

    Chapter 4

    Endocrine, nutritional and metabolic diseases (E00-E89)

  2. 2

    Section

    Metabolic disorders (E70-E88)

  3. 3

    Category E88

    Other and unspecified metabolic disorders

  4. 4

    Code E88

    Other and unspecified metabolic disorders

More specific choices

Codes under E88

E88 is a non-billable category. Choose the child code that best matches the documented diagnosis.

E88.0

Disorders of plasma-protein metabolism, not elsewhere classified

E88.1

Lipodystrophy, not elsewhere classified

E88.2

Lipomatosis, not elsewhere classified

E88.3

Tumor lysis syndrome

E88.4

Mitochondrial metabolism disorders

E88.8

Other specified metabolic disorders

E88.9

Metabolic disorder, unspecified

E88.A

Wasting disease (syndrome) due to underlying condition

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for E88.

Code first

No “code first” instruction is listed for E88.

Use additional code

  • codes for associated conditions

Excludes1

Conditions that should not be reported together with this code.

  • histiocytosis X (chronic) (C96.6)

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for E88.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

Publisher

Vero Scribe Inc.

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code E88 mean?

E88 is the FY 2027 U.S. ICD-10-CM code for “Other and unspecified metabolic disorders.”

Is E88 a billable or specific ICD-10-CM code?

No. E88 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is E88 located in ICD-10-CM?

E88 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Metabolic disorders (E70-E88) (E70–E88), under category E88, Other and unspecified metabolic disorders.

What coding notes are listed for E88?

No inclusion terms are listed for E88 in this reference record. No code-first instruction is listed. Additional-code instructions: codes for associated conditions. Excludes1 notes: histiocytosis X (chronic) (C96.6). No Excludes2 note is listed.

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