E88.4 ICD-10-CM Code: Mitochondrial metabolism disorders
E88.4 isn’t billable on its own. Choose one of the 5 billable codes beneath it, the one the documentation supports.
Official description
E88.4Mitochondrial metabolism disorders
ICD-10-CM diagnosis code · United States clinical modification
Billable codes under E88.4
E88.4 can’t be reported on its own. Choose the code below that matches what the note documents.
Where E88.4 sits
- 1
Chapter 4
Endocrine, nutritional and metabolic diseases (E00-E89)
- 2
Section
Metabolic disorders (E70-E88)
- 3
Category E88
Other and unspecified metabolic disorders
- 4
Code E88.4
Mitochondrial metabolism disorders
Notes for this code
Inclusion terms
No inclusion terms are listed for E88.4.
Code first
No “code first” instruction is listed for E88.4.
Use additional code
No “use additional code” instruction is listed for E88.4.
Excludes1
Conditions that should not be reported together with this code.
- disorders of pyruvate metabolism (E74.4)
- Kearns-Sayre syndrome (H49.81)
- Leber's disease (H47.22)
- Leigh's encephalopathy (G31.82)
- Mitochondrial myopathy, NEC (G71.3)
- Reye's syndrome (G93.7)
Excludes2
Conditions not included here that may be reported separately when present.
No Excludes2 note is listed for E88.4.
Source and release
- Data release
- U.S. ICD-10-CM · FY 2027
- Effective date
- Oct 1, 2026
- Publisher
- Vero Scribe Inc.
This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.
Frequently asked questions
What does ICD-10-CM code E88.4 mean?
E88.4 is the FY 2027 U.S. ICD-10-CM code for “Mitochondrial metabolism disorders.”
Is E88.4 a billable or specific ICD-10-CM code?
No. E88.4 has 5 billable codes beneath it in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.
Where is E88.4 located in ICD-10-CM?
E88.4 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Metabolic disorders (E70-E88) (E70–E88), under category E88, Other and unspecified metabolic disorders.
What coding notes are listed for E88.4?
No inclusion terms are listed for E88.4 in this reference record. No code-first instruction is listed. Excludes1 notes: disorders of pyruvate metabolism (E74.4); Kearns-Sayre syndrome (H49.81); Leber's disease (H47.22); Leigh's encephalopathy (G31.82); Mitochondrial myopathy, NEC (G71.3); Reye's syndrome (G93.7). No Excludes2 note is listed.