U.S. ICD-10-CM · FY 2027

D46 ICD-10-CM Code: Myelodysplastic syndromes

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

D46

Myelodysplastic syndromes

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where D46 sits

  1. 1

    Chapter 2

    Neoplasms (C00-D49)

  2. 2

    Section

    Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

  3. 3

    Category D46

    Myelodysplastic syndromes

  4. 4

    Code D46

    Myelodysplastic syndromes

More specific choices

Codes under D46

D46 is a non-billable category. Choose the child code that best matches the documented diagnosis.

D46.0

Refractory anemia without ring sideroblasts, so stated

D46.1

Refractory anemia with ring sideroblasts

D46.2

Refractory anemia with excess of blasts [RAEB]

D46.4

Refractory anemia, unspecified

D46.9

Myelodysplastic syndrome, unspecified

D46.A

Refractory cytopenia with multilineage dysplasia

D46.B

Refractory cytopenia with multilineage dysplasia and ring sideroblasts

D46.C

Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality

D46.Z

Other myelodysplastic syndromes

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for D46.

Code first

No “code first” instruction is listed for D46.

Use additional code

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for D46.

Excludes2

Conditions not included here that may be reported separately when present.

  • drug-induced aplastic anemia (D61.1)

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

Publisher

Vero Scribe Inc.

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code D46 mean?

D46 is the FY 2027 U.S. ICD-10-CM code for “Myelodysplastic syndromes.”

Is D46 a billable or specific ICD-10-CM code?

No. D46 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is D46 located in ICD-10-CM?

D46 is listed in Chapter 2, Neoplasms (C00-D49), within Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48) (D37–D48), under category D46, Myelodysplastic syndromes.

What coding notes are listed for D46?

No inclusion terms are listed for D46 in this reference record. No code-first instruction is listed. Additional-code instructions: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). No Excludes1 note is listed. Excludes2 notes: drug-induced aplastic anemia (D61.1).

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