D46.21 ICD-10-CM Code: Refractory anemia with excess of blasts 1
D46.21 is the billable ICD-10-CM code for “Refractory anemia with excess of blasts 1” in the FY 2027 U.S. code set, effective Oct 1, 2026.
Official description
D46.21Refractory anemia with excess of blasts 1
ICD-10-CM diagnosis code · United States clinical modification
Where D46.21 sits
- 1
Chapter 2
Neoplasms (C00-D49)
- 2
Section
Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
- 3
Category D46
Myelodysplastic syndromes
- 4
Subcategory D46.2
Refractory anemia with excess of blasts [RAEB]
- 5
Code D46.21
Refractory anemia with excess of blasts 1
Notes for this code
Inclusion terms
- RAEB 1
Code first
No “code first” instruction is listed for D46.21.
Use additional code
No “use additional code” instruction is listed for D46.21.
Excludes1
Conditions that should not be reported together with this code.
No Excludes1 note is listed for D46.21.
Excludes2
Conditions not included here that may be reported separately when present.
No Excludes2 note is listed for D46.21.
Source and release
- Data release
- U.S. ICD-10-CM · FY 2027
- Effective date
- Oct 1, 2026
- Publisher
- Vero Scribe Inc.
This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.
Frequently asked questions
What does ICD-10-CM code D46.21 mean?
D46.21 is the FY 2027 U.S. ICD-10-CM code for “Refractory anemia with excess of blasts 1.”
Is D46.21 a billable or specific ICD-10-CM code?
Yes. In the FY 2027 reference data used on this page, D46.21 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.
Where is D46.21 located in ICD-10-CM?
D46.21 is listed in Chapter 2, Neoplasms (C00-D49), within Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48) (D37–D48), under category D46, Myelodysplastic syndromes and subcategory D46.2, Refractory anemia with excess of blasts [RAEB].
What coding notes are listed for D46.21?
Its listed inclusion terms are RAEB 1. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.