R65 ICD-10-CM Code: Symptoms and signs specifically associated with systemic inflammation and infection
A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.
Official description
R65Symptoms and signs specifically associated with systemic inflammation and infection
ICD-10-CM diagnosis code · United States clinical modification
Where R65 sits
- 1
Chapter 18
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
- 2
Section
General symptoms and signs (R50-R69)
- 3
Category R65
Symptoms and signs specifically associated with systemic inflammation and infection
- 4
Code R65
Symptoms and signs specifically associated with systemic inflammation and infection
Codes under R65
R65 is a non-billable category. Choose the child code that best matches the documented diagnosis.
Notes for this code
Inclusion terms
No inclusion terms are listed for R65.
Code first
No “code first” instruction is listed for R65.
Use additional code
No “use additional code” instruction is listed for R65.
Excludes1
Conditions that should not be reported together with this code.
No Excludes1 note is listed for R65.
Excludes2
Conditions not included here that may be reported separately when present.
No Excludes2 note is listed for R65.
Source and release
- Data release
- U.S. ICD-10-CM · FY 2027
- Effective date
- Oct 1, 2026
- Publisher
- Vero Scribe Inc.
This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.
Frequently asked questions
What does ICD-10-CM code R65 mean?
R65 is the FY 2027 U.S. ICD-10-CM code for “Symptoms and signs specifically associated with systemic inflammation and infection.”
Is R65 a billable or specific ICD-10-CM code?
No. R65 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.
Where is R65 located in ICD-10-CM?
R65 is listed in Chapter 18, Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), within General symptoms and signs (R50-R69) (R50–R69), under category R65, Symptoms and signs specifically associated with systemic inflammation and infection.
What coding notes are listed for R65?
No inclusion terms are listed for R65 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.