U.S. ICD-10-CM · FY 2027

R53 ICD-10-CM Code: Malaise and fatigue

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

R53

Malaise and fatigue

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where R53 sits

  1. 1

    Chapter 18

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

  2. 2

    Section

    General symptoms and signs (R50-R69)

  3. 3

    Category R53

    Malaise and fatigue

  4. 4

    Code R53

    Malaise and fatigue

More specific choices

Codes under R53

R53 is a non-billable category. Choose the child code that best matches the documented diagnosis.

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for R53.

Code first

No “code first” instruction is listed for R53.

Use additional code

No “use additional code” instruction is listed for R53.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for R53.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for R53.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code R53 mean?

R53 is the FY 2027 U.S. ICD-10-CM code for “Malaise and fatigue.”

Is R53 a billable or specific ICD-10-CM code?

No. R53 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is R53 located in ICD-10-CM?

R53 is listed in Chapter 18, Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99), within General symptoms and signs (R50-R69) (R50–R69), under category R53, Malaise and fatigue.

What coding notes are listed for R53?

No inclusion terms are listed for R53 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.

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