U.S. ICD-10-CM · FY 2027

E22 ICD-10-CM Code: Hyperfunction of pituitary gland

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

E22

Hyperfunction of pituitary gland

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where E22 sits

  1. 1

    Chapter 4

    Endocrine, nutritional and metabolic diseases (E00-E89)

  2. 2

    Section

    Disorders of other endocrine glands (E20-E35)

  3. 3

    Category E22

    Hyperfunction of pituitary gland

  4. 4

    Code E22

    Hyperfunction of pituitary gland

More specific choices

Codes under E22

E22 is a non-billable category. Choose the child code that best matches the documented diagnosis.

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for E22.

Code first

No “code first” instruction is listed for E22.

Use additional code

No “use additional code” instruction is listed for E22.

Excludes1

Conditions that should not be reported together with this code.

  • Cushing's syndrome (E24.-)
  • Nelson's syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing's disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for E22.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code E22 mean?

E22 is the FY 2027 U.S. ICD-10-CM code for “Hyperfunction of pituitary gland.”

Is E22 a billable or specific ICD-10-CM code?

No. E22 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is E22 located in ICD-10-CM?

E22 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Disorders of other endocrine glands (E20-E35) (E20–E35), under category E22, Hyperfunction of pituitary gland.

What coding notes are listed for E22?

No inclusion terms are listed for E22 in this reference record. No code-first instruction is listed. Excludes1 notes: Cushing's syndrome (E24.-); Nelson's syndrome (E24.1); overproduction of ACTH not associated with Cushing's disease (E27.0); overproduction of pituitary ACTH (E24.0); overproduction of thyroid-stimulating hormone (E05.8-). No Excludes2 note is listed.

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