U.S. ICD-10-CM · FY 2027

C22 ICD-10-CM Code: Malignant neoplasm of liver and intrahepatic bile ducts

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

C22

Malignant neoplasm of liver and intrahepatic bile ducts

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where C22 sits

  1. 1

    Chapter 2

    Neoplasms (C00-D49)

  2. 2

    Section

    Malignant neoplasms of digestive organs (C15-C26)

  3. 3

    Category C22

    Malignant neoplasm of liver and intrahepatic bile ducts

  4. 4

    Code C22

    Malignant neoplasm of liver and intrahepatic bile ducts

More specific choices

Codes under C22

C22 is a non-billable category. Choose the child code that best matches the documented diagnosis.

C22.0

Liver cell carcinoma

C22.1

Intrahepatic bile duct carcinoma

C22.2

Hepatoblastoma

C22.3

Angiosarcoma of liver

C22.4

Other sarcomas of liver

C22.7

Other specified carcinomas of liver

C22.8

Malignant neoplasm of liver, primary, unspecified as to type

C22.9

Malignant neoplasm of liver, not specified as primary or secondary

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for C22.

Code first

No “code first” instruction is listed for C22.

Use additional code

  • code to identify:
  • alcohol abuse and dependence (F10.-)
  • hepatitis B (B16.-, B18.0-B18.1)
  • hepatitis C (B17.1-, B18.2)

Excludes1

Conditions that should not be reported together with this code.

  • malignant neoplasm of biliary tract NOS (C24.9)
  • secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for C22.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

Publisher

Vero Scribe Inc.

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code C22 mean?

C22 is the FY 2027 U.S. ICD-10-CM code for “Malignant neoplasm of liver and intrahepatic bile ducts.”

Is C22 a billable or specific ICD-10-CM code?

No. C22 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.

Where is C22 located in ICD-10-CM?

C22 is listed in Chapter 2, Neoplasms (C00-D49), within Malignant neoplasms of digestive organs (C15-C26) (C15–C26), under category C22, Malignant neoplasm of liver and intrahepatic bile ducts.

What coding notes are listed for C22?

No inclusion terms are listed for C22 in this reference record. No code-first instruction is listed. Additional-code instructions: code to identify:; alcohol abuse and dependence (F10.-); hepatitis B (B16.-, B18.0-B18.1); hepatitis C (B17.1-, B18.2). Excludes1 notes: malignant neoplasm of biliary tract NOS (C24.9); secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7). No Excludes2 note is listed.

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