Y53.0 ICD-10-CA code: Histamine H2-receptor antagonists causing adverse effect in therapeutic use

Y53.0 is the ICD-10-CA code for “Histamine H2-receptor antagonists causing adverse effect in therapeutic use” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.

Official description

Y53.0

Histamine H2-receptor antagonists causing adverse effect in therapeutic use

Short description: Histamine H2 receptor antgnst adv eff Rx

ICD-10-CA · Canada · Also written Y530

Notes for Y53.0

As CIHI prints them, with any note Y53.0 takes from the headings above it.

Includes

Complications of medical devicescorrect drug properly administered in therapeutic or prophylactic dosage as the cause of any adverse effectmisadventures to patients during surgical and medical caresurgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedureFrom Y40-Y84 Complications of medical and surgical care

Excludes

Conditions classified elsewhere.

Accidents in the technique of administration of drugs, medicaments and biological substances in medical and surgical procedures (Y60-Y69)From Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
Accidental overdose of drug or wrong drug given or taken in error (X40-X44)From Y40-Y84 Complications of medical and surgical care

Note

For list of specific drugs classified under the fourth-character subdivisions, see Table of drugs and chemicals in Alphabetical Index.From Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
This chapter, which in previous revisions of ICD constituted a supplementary classification, permits the classification of environmental events and circumstances as the cause of injury, poisoning and other adverse effects. Where a code from this section is applicable, it is intended that it shall be used in addition to a code from another chapter of the Classification indicating the nature of the condition. Most often, the condition will be classifiable to Chapter XIX, Injury, poisoning and certain other consequences of external causes (S00-T98). Causes of death should preferably be tabulated according to both Chapter XIX and Chapter XX, but if only one code is tabulated then the code from Chapter XX should be used in preference. Other conditions that may be stated to be due to external causes are classified in Chapters I to XVIII. For these conditions, codes from Chapter XX should be used to provide additional information for multiple-condition analysis only.From Chapter 20: External causes of morbidity and mortality (V01-Y98)

Where Y53.0 sits

1ChapterChapter 20: External causes of morbidity and mortality (V01-Y98)
2Block Y40-Y84Complications of medical and surgical care
3Block Y40-Y59Drugs, medicaments and biological substances causing adverse effects in therapeutic use
4Category Y53Agents primarily affecting the gastrointestinal system
5Valid code Y53.0Histamine H2-receptor antagonists causing adverse effect in therapeutic use

Source and release

Data release: ICD-10-CA · FY 2026–2027
Effective date: Apr 1, 2026
Publisher: CIHI

This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

See Y53.0 in the CIHI source

Frequently asked questions

What does ICD-10-CA code Y53.0 mean?

Y53.0 is the ICD-10-CA code for “Histamine H2-receptor antagonists causing adverse effect in therapeutic use” in CIHI’s ICD-10-CA FY 2026–2027 release.

Where is Y53.0 in ICD-10-CA?

Y53.0 sits under Y53 Agents primarily affecting the gastrointestinal system, within Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use, within Y40-Y84 Complications of medical and surgical care, within Chapter 20: External causes of morbidity and mortality (V01-Y98).

What coding notes apply to Y53.0?

ICD-10-CA lists Note, Excludes, Includes notes for Y53.0, including those from the headings it sits under. They are listed on this page with where each one comes from.

Which ICD-10-CA release does this page use?

It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.

View Y53