Literature review, from one question to a cited synthesis.

Ask one question, and get the studies back in a table. Design, size, finding, and level for each, then a short synthesis with every line cited.

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Table the evidence on a Mediterranean diet and heart disease.

StudyDesignnFindingLevel

PREDIMEDN Engl J Med 2018RCT7,447Fewer major CV eventsL1

CORDIOPREVLancet 2022RCT1,002Fewer events after coronary diseaseL1

Women’s Health StudyJAMA Netw Open 2018Cohort25,994About 25% lower CVD riskL2

A Mediterranean diet lowered major cardiovascular events, before and after coronary disease. pubmedL1 pubmedL1

In women followed up to 12 years, high adherence went with about a quarter less CVD. pubmedL2

Ask one question
In plain words, with its purpose.
Get the table
Design, size, finding, and level.
Read the synthesis
Every line closed by its sources.
Write it up
An outline, background, or summary.

One question, five studies, one evidence table.

Ask for a review, and the studies come back tabled, then summarized with every line cited.

Literature review: time-restricted eating for weight loss. Table the studies, then summarize.

Semnani-Azad et al.BMJ · 2025Network meta-analysis99 trials · 6,582VariedTime-restricted eating matched continuous calorie restriction; only alternate-day fasting did slightly better.L1

Lin et al.Ann Intern Med · 2023Randomized trial9012 monthsAn 8-hour window without calorie counting: 4.6 kg lost vs control, similar to calorie restriction.L1

Liu et al.N Engl J Med · 2022Randomized trial13912 monthsAdding an 8-hour window to calorie restriction: 8.0 vs 6.3 kg lost, not significant.L1

Jamshed et al.JAMA Intern Med · 2022Randomized trial9014 weeksEarly eating (7 am to 3 pm) with energy restriction: 2.3 kg more lost.L1

Lowe et al. (TREAT)JAMA Intern Med · 2020Randomized trial11612 weeksA 16:8 window alone vs three meals a day: no difference in weight.L1

Synthesis

Time-restricted eating leads to modest weight loss, about as much as daily calorie restriction. pubmedL1 pubmedL1 Added to calorie restriction, or tried alone against regular meals, a shorter window added no weight loss. pubmedL1 pubmedL1 Only one trial found extra loss on top of calorie restriction; it used an early window and ran 14 weeks. pubmedL1

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Whatever the review is for, from journal club to a patient’s question.

Journal club

MINT and the transfusion threshold after MI

The trial on the table, set beside the one before it.

Journal club on MINT. Set it beside the trial before it.

MINTN Engl J Med · 2023RCT · 3,504MI or death at 30 days: 16.9% restrictive vs 14.5% liberal, not significantL1
REALITYJAMA · 2021RCT · 668Restrictive noninferior for 30-day MACE: 11.0% vs 14.0%L1

Neither trial showed one threshold clearly better after MI with anemia. pubmedL1 pubmedL1

MINT leaned toward a liberal threshold, and harm from a restrictive one cannot be excluded. pubmedL1

Background for a QI project on surgical safety checklists.

Haynes et al.N Engl J Med · 2009Before-after · 7,688Deaths 1.5% to 0.8%; complications 11.0% to 7.0%L2
Urbach et al.N Engl J Med · 2014Cohort · 215,711 proceduresNo significant change in deaths or complicationsL2

In the WHO pilot across 8 hospitals, deaths and complications fell after the checklist. pubmedL2

Adopted across 101 Ontario hospitals, it brought no significant change. pubmedL2

We are updating our delirium prevention protocol. What works?

Burton et al.Cochrane Database Syst Rev · 2021Systematic review · 22 trials · 5,718Multicomponent prevention: delirium 10.5% vs 18.4%L1
Hshieh et al.JAMA Intern Med · 2015Meta-analysis · 14 studiesDelirium odds about halved; fewer fallsL1

Multicomponent, non-drug prevention cuts new delirium by about 40% on general wards. pubmedL1

It also lowers falls (OR 0.38). pubmedL1

My patient asks whether cranberry prevents her UTIs.

Williams et al.Cochrane Database Syst Rev · 2023Systematic review · 50 trials · 8,857Fewer UTIs in women with recurrent UTI (RR 0.74), children, and after proceduresL1
Fu et al.J Nutr · 2017Meta-analysis · 7 trials · 1,498Recurrence risk down 26%L1

For women with recurrent UTIs, cranberry products probably lower the risk by about a quarter. pubmedL1 pubmedL1

Little or no benefit in older adults in care or in pregnancy. pubmedL1

A synthesis that says what the studies cannot.

Conflicts, called out

When trials point different ways, the synthesis says so and cites each side.

Limits, named

Small samples and short follow-up are stated, not buried.

Gaps, flagged

What the evidence has not tested yet, with the source that says so.

Review the evidence free

Bring your own papers

Attach PDFs with Upload Files, or pick a Library collection your team shares. The synthesis names each file it draws on.

From review to write-up

Ask for a journal club outline, a QI background section, or a protocol summary. Vero drafts it from the same studies, citations in place.

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Literature reviews in Vero.

Can Vero do a literature review?

Yes. Ask your clinical question and ask for the studies in a table. Vero lists each study’s design, size, finding, and level of evidence, then writes a short synthesis with every source cited.

What goes in the evidence table?

Whatever you ask for. A typical table has the study, journal and year, design, sample size, follow-up, main finding, and level of evidence.

Can I review papers I already have?

Yes. Attach PDFs with Upload Files, or pick a Library collection your team shares. The synthesis names each file it draws on.

What happens when studies disagree?

The synthesis says so and cites each side. It also names the limits that matter, such as small samples or short follow-up.

Can it help me write up the review?

Yes. Ask for a journal club outline, the background section of a QI project, or a summary for a protocol update. Vero drafts it from the same studies and keeps the citations.

Which sources go into a review?

Systematic reviews and meta-analyses, randomized trials and clinical studies, peer-reviewed journals, clinical guidelines, and drug references. Never forums or blogs.

How do I tell strong studies from weak ones?

Each trial result shows a level from its design. Systematic reviews and randomized trials are L1, cohort studies L2, case-control studies and case series L3, and expert opinion L4.

Does a literature review cost anything?

Vero Evidence comes with every plan. Free includes 10 actions a month with no credit card, and Pro is unlimited.

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Related ways to work with evidence.

Peer-reviewed article search

The papers that answer your question, without query syntax.

Search peer-reviewed articles

Evidence summaries

The bottom line of a topic, sourced and graded.

See evidence summaries

PICO questions

Frame a clinical question, then answer it.

Write a PICO question

Research alerts

New research when the question comes up.

Keep up with research

Start with one question. Finish with a cited synthesis.

Studies tabled, graded, and summarized for journal club, a QI project, or your next protocol.

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