S3855 HCPCS Level II code: Genetic testing for detection of mutations in the presenilin - 1 gene
CMS terminated S3855: its last date of service was Dec 31, 2014. It stays here for looking up older claims; newer services need a current code.
Official description
S3855Genetic testing for detection of mutations in the presenilin - 1 gene
Short description: Gene test presenilin-1 gene
HCPCS · United States
Medicare details
The indicators CMS publishes with S3855 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Not payable by Medicare
- Medicare pricing
- Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)
- Type of service
- Other medical items or services
- BETOS category
- Undefined codes
- Added
- Jan 1, 2007
- Terminated after
- Dec 31, 2014
Where S3855 sits
- 1S codesTemporary national codes (non-Medicare)
- 2Terminated S3855Genetic testing for detection of mutations in the presenilin - 1 gene
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
Is HCPCS code S3855 still valid?
No. CMS terminated S3855; its last date of service was Dec 31, 2014. It is listed for looking up services from before then. Use a current code for newer services.
Does Medicare cover S3855?
CMS lists S3855’s Medicare coverage as “Not payable by Medicare” and its pricing as “Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside S3855
All S codesS3846Genetic testing for hemoglobin e beta-thalassemiaS3849Genetic testing for niemann-pick diseaseS3850Genetic testing for sickle cell anemiaS3852Dna analysis for apoe epsilon 4 allele for susceptibility to alzheimer's diseaseS3853Genetic testing for myotonic muscular dystrophyS3854Gene expression profiling panel for use in the management of breast cancer treatmentS3861Genetic testing, sodium channel, voltage-gated, type v, alpha subunit (scn5a) and variants for suspected brugada syndromeS3865Comprehensive gene sequence analysis for hypertrophic cardiomyopathyS3866Genetic analysis for a specific gene mutation for hypertrophic cardiomyopathy (hcm) in an individual with a known hcm mutation in the familyS3870Comparative genomic hybridization (cgh) microarray testing for developmental delay, autism spectrum disorder and/or intellectual disabilityS3890Dna analysis, fecal, for colorectal cancer screeningS3900Surface electromyography (emg)