S3850 HCPCS Level II code: Genetic testing for sickle cell anemia
S3850 is the HCPCS code for “Genetic testing for sickle cell anemia” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
S3850Genetic testing for sickle cell anemia
Short description: Gene test sickle cell
HCPCS · United States
Medicare details
The indicators CMS publishes with S3850 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Not payable by Medicare
- Medicare pricing
- Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)
- Type of service
- Other medical items or services
- BETOS category
- Undefined codes
- Added
- Jul 1, 2003
Where S3850 sits
- 1S codesTemporary national codes (non-Medicare)
- 2Active code S3850Genetic testing for sickle cell anemia
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code S3850 mean?
S3850 is the HCPCS code for “Genetic testing for sickle cell anemia” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover S3850?
CMS lists S3850’s Medicare coverage as “Not payable by Medicare” and its pricing as “Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside S3850
All S codesS3841Genetic testing for retinoblastomaS3842Genetic testing for von hippel-lindau diseaseS3844Dna analysis of the connexin 26 gene (gjb2) for susceptibility to congenital, profound deafnessS3845Genetic testing for alpha-thalassemiaS3846Genetic testing for hemoglobin e beta-thalassemiaS3849Genetic testing for niemann-pick diseaseS3852Dna analysis for apoe epsilon 4 allele for susceptibility to alzheimer's diseaseS3853Genetic testing for myotonic muscular dystrophyS3854Gene expression profiling panel for use in the management of breast cancer treatmentS3855Genetic testing for detection of mutations in the presenilin - 1 geneS3861Genetic testing, sodium channel, voltage-gated, type v, alpha subunit (scn5a) and variants for suspected brugada syndromeS3865Comprehensive gene sequence analysis for hypertrophic cardiomyopathy