S2120 HCPCS Level II code: Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation
S2120 is the HCPCS code for “Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
S2120Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation
Short description: Low density lipoprotein(ldl)
HCPCS · United States
Notes for S2120
As CMS prints them, with any note S2120 takes from the headings above it.
Note
- CMS processing note 0088: "S" CODES ARE UNIQUE TEMPORARY CODES ESTABLISHED BY BCBSA AND HIAA FOR PRIVATE PAYOR USE. THEY ARE NOT VALID NOR PAYABLE BY MEDICARE.
Medicare details
The indicators CMS publishes with S2120 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Not payable by Medicare
- Medicare pricing
- Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)
- Type of service
- Other medical items or services
- BETOS category
- Undefined codes
- Added
- Jan 1, 2001
Where S2120 sits
- 1S codesTemporary national codes (non-Medicare)
- 2Active code S2120Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code S2120 mean?
S2120 is the HCPCS code for “Low density lipoprotein (ldl) apheresis using heparin-induced extracorporeal ldl precipitation” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover S2120?
CMS lists S2120’s Medicare coverage as “Not payable by Medicare” and its pricing as “Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside S2120
All S codesS2103Adrenal tissue transplant to brainS2107Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatmentS2112Arthroscopy, knee, surgical for harvesting of cartilage (chondrocyte cells)S2115Osteotomy, periacetabular, with internal fixationS2117Arthroereisis, subtalarS2118Metal-on-metal total hip resurfacing, including acetabular and femoral componentsS2140Cord blood harvesting for transplantation, allogeneicS2142Cord blood-derived stem-cell transplantation, allogeneicS2150Bone marrow or blood-derived stem cells (peripheral or umbilical), allogeneic or autologous, harvesting, transplantation, and related complications; including: pheresis and cell…S2152Solid organ(s), complete or segmental, single organ or combination of organs; deceased or living donor(s), procurement, transplantation, and related complications; including…S2202EchosclerotherapyS2205Minimally invasive direct coronary artery bypass surgery involving mini-thoracotomy or mini-sternotomy surgery, performed under direct vision; using arterial graft(s), single…