S2107 HCPCS Level II code: Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment

S2107 is the HCPCS code for “Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment” in CMS’s October 2026 release, in effect from Oct 1, 2026.

Official description

S2107

Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment

Short description: Adoptive immunotherapy

HCPCS · United States

Medicare details

The indicators CMS publishes with S2107 in its October 2026 file. They describe Medicare’s handling, not another payer’s.

Medicare coverage
Not payable by Medicare
Medicare pricing
Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)
Type of service
Other medical items or services
BETOS category
Undefined codes
Added
Apr 1, 2002

Where S2107 sits

  1. 1S codesTemporary national codes (non-Medicare)
  2. 2Active code S2107Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment

Source and release

Data release
HCPCS Level II · October 2026
Effective date
Oct 1, 2026
Publisher
CMS

This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

Frequently asked questions

What does HCPCS code S2107 mean?

S2107 is the HCPCS code for “Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment” in CMS’s HCPCS Level II October 2026 release.

Does Medicare cover S2107?

CMS lists S2107’s Medicare coverage as “Not payable by Medicare” and its pricing as “Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.

Which HCPCS Level II release does this page use?

It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.