R65.2 ICD-10-CA code: Systemic inflammatory response syndrome of noninfectious origin without organ failure
R65.2 is the ICD-10-CA code for “Systemic inflammatory response syndrome of noninfectious origin without organ failure” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.
Official description
R65.2Systemic inflammatory response syndrome of noninfectious origin without organ failure
Short description: SIRS noninfectious w/out organ failure
ICD-10-CA · Canada · Also written R652
Index terms
Entries in CIHI’s alphabetical index that lead to R65.2. Searching the index by the condition the note names is how coders reach this code.
- Systemic Inflammatory Response Syndrome (SIRS), noninfectious origin, without organ failure
- Syndrome, systemic inflammatory response (SIRS) as a result of disease classified elsewhere, noninfectious origin, without organ failure
Notes for R65.2
As CIHI prints them, with any note R65.2 takes from the headings above it.
Use additional code
Add a code for this detail when the note documents it.
- Use additional code to identify underlying cause such as trauma or sepsisFrom R65 Systemic inflammatory response syndrome [SIRS]
Excludes
Conditions classified elsewhere.
- Abnormal findings on antenatal screening of mother (O28.-)certain conditions originating in the perinatal period (P00-P96)From Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Note
- This category should never be used in primary coding. The category is for use in multiple coding to identify this condition resulting from any cause.From R65 Systemic inflammatory response syndrome [SIRS]
- Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated "not otherwise specified", "unknown etiology" or "transient". The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.The conditions and signs or symptoms included in categories (R00-R99) consist of:(a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;(b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;(c) provisional diagnoses in a patient who failed to return for further investigation or care;(d) cases referred elsewhere for investigation or treatment before the diagnosis was made;(e) cases in which a more precise diagnosis was not available for any other reason;(f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.From Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Where R65.2 sits
- 1ChapterChapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
- 2Block R50-R69General symptoms and signs
- 3Category R65Systemic inflammatory response syndrome [SIRS]
- 4Valid code R65.2Systemic inflammatory response syndrome of noninfectious origin without organ failure
Source and release
- Data release
- ICD-10-CA · FY 2026–2027
- Effective date
- Apr 1, 2026
- Publisher
- CIHI
This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does ICD-10-CA code R65.2 mean?
R65.2 is the ICD-10-CA code for “Systemic inflammatory response syndrome of noninfectious origin without organ failure” in CIHI’s ICD-10-CA FY 2026–2027 release.
Where is R65.2 in ICD-10-CA?
R65.2 sits under R65 Systemic inflammatory response syndrome [SIRS], within R50-R69 General symptoms and signs, within Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).
What coding notes apply to R65.2?
ICD-10-CA lists Note, Use additional code, Excludes notes for R65.2, including those from the headings it sits under. They are listed on this page with where each one comes from.
Which ICD-10-CA release does this page use?
It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside R65.2
View R65R65.0Systemic inflammatory response syndrome of infectious origin without organ failureR65.1Systemic inflammatory response syndrome of infectious origin with acute organ failureR65.3Systemic inflammatory response syndrome of noninfectious origin with acute organ failureR65.9Systemic inflammatory response syndrome, unspecified