M32.1 ICD-10-CA code: Systemic lupus erythematosus with organ or system involvement

M32.1 is the ICD-10-CA code for “Systemic lupus erythematosus with organ or system involvement” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.

Official description

M32.1

Systemic lupus erythematosus with organ or system involvement

Short description: SLE with organ or system involvement

ICD-10-CA · Canada · Also written M321

Notes for M32.1

As CIHI prints them, with any note M32.1 takes from the headings above it.

Includes

  • Libman-Sacks disease (I39.-*)Lupus pericarditis (I32.8*)Systemic lupus erythematosus with:• kidney involvement (N08.5*,N16.4*)• lung involvement (J99.1*)
  • Autoimmune disease:• NOS• systemiccollagen (vascular) disease:• NOS• systemicFrom M30-M36 Systemic connective tissue disorders

Excludes

Conditions classified elsewhere.

  • Lupus erythematosus (discoid)(NOS) (L93.0)From M32 Systemic lupus erythematosus
  • Antiphospholipid syndrome (D68.6)autoimmune disease, single organ or single cell-type (code to relevant condition category)From M30-M36 Systemic connective tissue disorders
  • Certain:• conditions originating in the perinatal period (P00-P96)• disorders of the temporomandibular joint (K07.6)• infectious and parasitic diseases (A00-B99)compartment syndrome (T79.6)complications of pregnancy, childbirth and the puerperium (O00-O99)congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)endocrine, nutritional and metabolic diseases (E00-E90)injury, poisoning and certain other consequences of external causes (S00-T98)neoplasms (C00-D48)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)From Chapter 13: Diseases of the musculoskeletal system and connective tissue (M00-M99)

Note

  • The following fifth characters represent the following sites of involvement:0 Multiple sites1 Shoulder region: clavical , scapula — joint acromioclavicular, glenohumeral, sternoclavicular2 Upper arm: humerus — elbow joint,3 Forearm: radius , ulna — wrist joint,4 Hand: carpus, fingers, metacarpus — joints between these bones,5 Pelvic region and thigh: buttock , femur , pelvis — joint hip , sacroiliac6 Lower leg: fibula , tibia — knee joint7 Ankle and foot: metatarsus, tarsus, toes — other joints in foot8 Other:head neck ribs skull trunk vertebral column9 Site unspecifiedFrom Chapter 13: Diseases of the musculoskeletal system and connective tissue (M00-M99)

Where M32.1 sits

  1. 1ChapterChapter 13: Diseases of the musculoskeletal system and connective tissue (M00-M99)
  2. 2Block M30-M36Systemic connective tissue disorders
  3. 3Category M32Systemic lupus erythematosus
  4. 4Valid code M32.1Systemic lupus erythematosus with organ or system involvement

Source and release

Data release
ICD-10-CA · FY 2026–2027
Effective date
Apr 1, 2026
Publisher
CIHI

This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

Frequently asked questions

What does ICD-10-CA code M32.1 mean?

M32.1 is the ICD-10-CA code for “Systemic lupus erythematosus with organ or system involvement” in CIHI’s ICD-10-CA FY 2026–2027 release.

Where is M32.1 in ICD-10-CA?

M32.1 sits under M32 Systemic lupus erythematosus, within M30-M36 Systemic connective tissue disorders, within Chapter 13: Diseases of the musculoskeletal system and connective tissue (M00-M99).

What coding notes apply to M32.1?

ICD-10-CA lists Includes, Excludes, Note notes for M32.1, including those from the headings it sits under. They are listed on this page with where each one comes from.

Which ICD-10-CA release does this page use?

It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.