E85.3 ICD-10-CA code: Secondary systemic amyloidosis

E85.3 is the ICD-10-CA code for “Secondary systemic amyloidosis” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.

Official description

E85.3

Secondary systemic amyloidosis

ICD-10-CA · Canada · Also written E853

Index terms

Entries in CIHI’s alphabetical index that lead to E85.3. Searching the index by the condition the note names is how coders reach this code.

  • Amyloidosis (generalized) (primary), systemic, secondary
  • Amyloidosis (generalized) (primary), hemodialysis associated

Notes for E85.3

As CIHI prints them, with any note E85.3 takes from the headings above it.

Includes

  • Haemodialysis-associated amyloidosis

Excludes

Conditions classified elsewhere.

  • Alzheimer's disease (G30.-)From E85 Amyloidosis
  • 5-alpha -reductase deficiency (E29.1)androgen resistance syndrome (E34.5)congenital adrenal hyperplasia (E25.0)Ehlers-Danlos syndrome (Q79.6)haemolytic anaemias due to enzyme disorders (D55.-)Marfan's syndrome (Q87.4)From E70-E90 Metabolic disorders
  • Complications of pregnancy, childbirth and the puerperium (O00-O99)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)transitory endocrine and metabolic disorders specific to fetus and newborn (P70-P74)From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)

Note

  • All neoplasms, whether functionally active or not, are classified in Chapter II. Appropriate codes in this chapter (i.e. E05.8)(E07.0) (E16-E31)(E34.-) may be used, if desired, as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)

Where E85.3 sits

  1. 1ChapterChapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
  2. 2Block E70-E90Metabolic disorders
  3. 3Category E85Amyloidosis
  4. 4Valid code E85.3Secondary systemic amyloidosis

Source and release

Data release
ICD-10-CA · FY 2026–2027
Effective date
Apr 1, 2026
Publisher
CIHI

This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

Frequently asked questions

What does ICD-10-CA code E85.3 mean?

E85.3 is the ICD-10-CA code for “Secondary systemic amyloidosis” in CIHI’s ICD-10-CA FY 2026–2027 release.

Where is E85.3 in ICD-10-CA?

E85.3 sits under E85 Amyloidosis, within E70-E90 Metabolic disorders, within Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90).

What coding notes apply to E85.3?

ICD-10-CA lists Includes, Excludes, Note notes for E85.3, including those from the headings it sits under. They are listed on this page with where each one comes from.

Which ICD-10-CA release does this page use?

It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.