E74.4 ICD-10-CA code: Disorders of pyruvate metabolism and gluconeogenesis
E74.4 is the ICD-10-CA code for “Disorders of pyruvate metabolism and gluconeogenesis” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.
Official description
E74.4Disorders of pyruvate metabolism and gluconeogenesis
Short description: Disrd pyruvate metab & gluconeogenesis
ICD-10-CA · Canada · Also written E744
Index terms
Entries in CIHI’s alphabetical index that lead to E74.4. Searching the index by the condition the note names is how coders reach this code.
- Disorder (of), gluconeogenesis
- Disorder (of), pyruvate metabolism
- Disorder (of), metabolism NEC, pyruvate
- Deficiency, deficient, pyruvate, carboxylase
- Deficiency, deficient, pyruvate, dehydrogenase
- Deficiency, deficient, phosphoenolpyruvate carboxykinase
Notes for E74.4
As CIHI prints them, with any note E74.4 takes from the headings above it.
Includes
- Deficiency of:• phosphoenolpyruvate carboxykinase• pyruvate• carboxylase• dehydrogenase
Excludes
Conditions classified elsewhere.
- With anaemia (D55.-)
- Diabetes mellitus (E10-E14)hypoglycaemia NOS (E16.2)increased secretion of glucagon (E16.3)mucopolysaccharidosis (E76.0-E76.3)From E74 Other disorders of carbohydrate metabolism
- 5-alpha -reductase deficiency (E29.1)androgen resistance syndrome (E34.5)congenital adrenal hyperplasia (E25.0)Ehlers-Danlos syndrome (Q79.6)haemolytic anaemias due to enzyme disorders (D55.-)Marfan's syndrome (Q87.4)From E70-E90 Metabolic disorders
- Complications of pregnancy, childbirth and the puerperium (O00-O99)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)transitory endocrine and metabolic disorders specific to fetus and newborn (P70-P74)From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
Note
- All neoplasms, whether functionally active or not, are classified in Chapter II. Appropriate codes in this chapter (i.e. E05.8)(E07.0) (E16-E31)(E34.-) may be used, if desired, as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
Where E74.4 sits
- 1ChapterChapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
- 2Block E70-E90Metabolic disorders
- 3Category E74Other disorders of carbohydrate metabolism
- 4Valid code E74.4Disorders of pyruvate metabolism and gluconeogenesis
Source and release
- Data release
- ICD-10-CA · FY 2026–2027
- Effective date
- Apr 1, 2026
- Publisher
- CIHI
This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does ICD-10-CA code E74.4 mean?
E74.4 is the ICD-10-CA code for “Disorders of pyruvate metabolism and gluconeogenesis” in CIHI’s ICD-10-CA FY 2026–2027 release.
Where is E74.4 in ICD-10-CA?
E74.4 sits under E74 Other disorders of carbohydrate metabolism, within E70-E90 Metabolic disorders, within Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90).
What coding notes apply to E74.4?
ICD-10-CA lists Includes, Excludes, Note notes for E74.4, including those from the headings it sits under. They are listed on this page with where each one comes from.
Which ICD-10-CA release does this page use?
It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.