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E72.2 ICD-10-CA code: Disorders of urea cycle metabolism

E72.2 is the ICD-10-CA code for “Disorders of urea cycle metabolism” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.

Official description

E72.2

Disorders of urea cycle metabolism

ICD-10-CA · Canada · Also written E722

Index terms

Entries in CIHI’s alphabetical index that lead to E72.2. Searching the index by the condition the note names is how coders reach this code.

  • Argininemia
  • Citrullinemia
  • Citrullinuria
  • Acidemia, argininosuccinic
  • Aciduria, argininosuccinic
  • Hyperammonemia (congenital)
  • Hyperaminoaciduria, arginine
  • Urea, cycle metabolism disorder
  • Disturbance, metabolism, ammonia
  • Disturbance, metabolism, arginine
  • Disturbance, metabolism, citrulline
  • Disturbance, metabolism, urea cycle
  • Disorder (of), urea cycle metabolism
  • Disturbance, metabolism, arginosuccinic acid
  • Deficiency, deficient, ornithine transcarbamylase (carbamoyltransferase)

Notes for E72.2

As CIHI prints them, with any note E72.2 takes from the headings above it.

Includes

  • ArgininaemiaArgininosuccinic aciduriaCitrullinaemiaHyperammonaemia

Excludes

Conditions classified elsewhere.

  • Disorders of ornithine metabolism (E72.4)
  • Abnormal findings without manifest disease (R70-R89)disorders of:• aromatic amino-acid metabolism (E70.-)• branched-chain amino-acid metabolism (E71.0-E71.2)• fatty-acid metabolism (E71.3)• purine and pyrimidine metabolism (E79.-)gout (M10.-)From E72 Other disorders of amino-acid metabolism
  • 5-alpha -reductase deficiency (E29.1)androgen resistance syndrome (E34.5)congenital adrenal hyperplasia (E25.0)Ehlers-Danlos syndrome (Q79.6)haemolytic anaemias due to enzyme disorders (D55.-)Marfan's syndrome (Q87.4)From E70-E90 Metabolic disorders
  • Complications of pregnancy, childbirth and the puerperium (O00-O99)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)transitory endocrine and metabolic disorders specific to fetus and newborn (P70-P74)From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)

Note

  • All neoplasms, whether functionally active or not, are classified in Chapter II. Appropriate codes in this chapter (i.e. E05.8)(E07.0) (E16-E31)(E34.-) may be used, if desired, as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)

Where E72.2 sits

  1. 1ChapterChapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
  2. 2Block E70-E90Metabolic disorders
  3. 3Category E72Other disorders of amino-acid metabolism
  4. 4Valid code E72.2Disorders of urea cycle metabolism

Source and release

Data release
ICD-10-CA · FY 2026–2027
Effective date
Apr 1, 2026
Publisher
CIHI

This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

See E72.2 in the CIHI source

Frequently asked questions

What does ICD-10-CA code E72.2 mean?

E72.2 is the ICD-10-CA code for “Disorders of urea cycle metabolism” in CIHI’s ICD-10-CA FY 2026–2027 release.

Where is E72.2 in ICD-10-CA?

E72.2 sits under E72 Other disorders of amino-acid metabolism, within E70-E90 Metabolic disorders, within Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90).

What coding notes apply to E72.2?

ICD-10-CA lists Includes, Excludes, Note notes for E72.2, including those from the headings it sits under. They are listed on this page with where each one comes from.

Which ICD-10-CA release does this page use?

It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.

Codes beside E72.2

E72.0Disorders of amino-acid transportE72.1Disorders of sulfur-bearing amino-acid metabolismE72.3Disorders of lysine and hydroxylysine metabolismE72.4Disorders of ornithine metabolismE72.5Disorders of glycine metabolismE72.8Other specified disorders of amino-acid metabolismE72.9Disorder of amino-acid metabolism, unspecified