E22.2 ICD-10-CA code: Syndrome of inappropriate secretion of antidiuretic hormone
E22.2 is the ICD-10-CA code for “Syndrome of inappropriate secretion of antidiuretic hormone” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.
Official description
E22.2Syndrome of inappropriate secretion of antidiuretic hormone
Short description: SIADH
ICD-10-CA · Canada · Also written E222
Index terms
Entries in CIHI’s alphabetical index that lead to E22.2. Searching the index by the condition the note names is how coders reach this code.
- Antidiuretic hormone syndrome
- Hypersecretion, hormone(s), antidiuretic
- Syndrome, inappropriate secretion of antidiuretic hormone
- Secretion, hormone, antidiuretic, inappropriate (syndrome)
Notes for E22.2
As CIHI prints them, with any note E22.2 takes from the headings above it.
Excludes
Conditions classified elsewhere.
- Cushing's syndrome (E24.-)Nelson's syndrome (E24.1)overproduction of:• ACTH not associated with Cushing's disease (E27.0)• pituitary ACTH (E24.0)• thyroid-stimulating hormone (E05.8)From E22 Hyperfunction of pituitary gland
- Galactorrhoea (N64.3)gynaecomastia (N62)From E20-E35 Disorders of other endocrine glands
- Complications of pregnancy, childbirth and the puerperium (O00-O99)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)transitory endocrine and metabolic disorders specific to fetus and newborn (P70-P74)From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
Note
- All neoplasms, whether functionally active or not, are classified in Chapter II. Appropriate codes in this chapter (i.e. E05.8)(E07.0) (E16-E31)(E34.-) may be used, if desired, as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.From Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
Where E22.2 sits
- 1ChapterChapter 4: Endocrine, nutritional and metabolic diseases (E00-E90)
- 2Block E20-E35Disorders of other endocrine glands
- 3Category E22Hyperfunction of pituitary gland
- 4Valid code E22.2Syndrome of inappropriate secretion of antidiuretic hormone
Source and release
- Data release
- ICD-10-CA · FY 2026–2027
- Effective date
- Apr 1, 2026
- Publisher
- CIHI
This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does ICD-10-CA code E22.2 mean?
E22.2 is the ICD-10-CA code for “Syndrome of inappropriate secretion of antidiuretic hormone” in CIHI’s ICD-10-CA FY 2026–2027 release.
Where is E22.2 in ICD-10-CA?
E22.2 sits under E22 Hyperfunction of pituitary gland, within E20-E35 Disorders of other endocrine glands, within Chapter 4: Endocrine, nutritional and metabolic diseases (E00-E90).
What coding notes apply to E22.2?
ICD-10-CA lists Excludes, Note notes for E22.2, including those from the headings it sits under. They are listed on this page with where each one comes from.
Which ICD-10-CA release does this page use?
It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.