D89.3 ICD-10-CA code: Immune reconstitution syndrome
D89.3 is the ICD-10-CA code for “Immune reconstitution syndrome” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.
Official description
D89.3Immune reconstitution syndrome
ICD-10-CA · Canada · Also written D893
Index terms
Entries in CIHI’s alphabetical index that lead to D89.3. Searching the index by the condition the note names is how coders reach this code.
- Immune reconstitution syndrome (inflammatory)
- Syndrome, immune reconstitution (inflammatory)
Notes for D89.3
As CIHI prints them, with any note D89.3 takes from the headings above it.
Includes
- Immune reconstitution inflammatory syndrome [IRIS]
- Defects in the complement systemimmunodeficiency disorders, except human immunodeficiency virus [HIV] diseasesarcoidosisFrom D80-D89 Certain disorders involving the immune mechanism
Use additional code
Add a code for this detail when the note documents it.
- Use additional external cause code (Chapter XX), to identify drug.
Excludes
Conditions classified elsewhere.
- Hyperglobulinaemia NOS (R77.1)monoclonal gammopathy of undetermined significance (MGUS) (D47.2)transplant failure and rejection (T86.-)From D89 Other disorders involving the immune mechanism, not elsewhere classified
- Autoimmune disease (systemic) NOS (M35.9)functional disorders of polymorphonuclear neutrophils (D71)human immunodeficiency virus [HIV] disease (B24)human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium (O98.7-)From D80-D89 Certain disorders involving the immune mechanism
- Autoimmune disease (systemic) NOS (M35.9)certain conditions originating in the perinatal period (P00-P96)complications of pregnancy, childbirth and the puerperium (O00-O99)congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)endocrine, nutritional and metabolic diseases (E00-E90)human immunodeficiency virus [HIV] disease (B24)injury, poisoning and certain other consequences of external causes (S00-T98)neoplasms (C00-D48)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)From Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Where D89.3 sits
- 1ChapterChapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- 2Block D80-D89Certain disorders involving the immune mechanism
- 3Category D89Other disorders involving the immune mechanism, not elsewhere classified
- 4Valid code D89.3Immune reconstitution syndrome
Source and release
- Data release
- ICD-10-CA · FY 2026–2027
- Effective date
- Apr 1, 2026
- Publisher
- CIHI
This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does ICD-10-CA code D89.3 mean?
D89.3 is the ICD-10-CA code for “Immune reconstitution syndrome” in CIHI’s ICD-10-CA FY 2026–2027 release.
Where is D89.3 in ICD-10-CA?
D89.3 sits under D89 Other disorders involving the immune mechanism, not elsewhere classified, within D80-D89 Certain disorders involving the immune mechanism, within Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).
What coding notes apply to D89.3?
ICD-10-CA lists Includes, Use additional code, Excludes notes for D89.3, including those from the headings it sits under. They are listed on this page with where each one comes from.
Which ICD-10-CA release does this page use?
It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.