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D68.5 ICD-10-CA code: Primary thrombophilia

D68.5 is the ICD-10-CA code for “Primary thrombophilia” in CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026.

Official description

D68.5

Primary thrombophilia

ICD-10-CA · Canada · Also written D685

Index terms

Entries in CIHI’s alphabetical index that lead to D68.5. Searching the index by the condition the note names is how coders reach this code.

  • Antithrombinemia
  • Thrombophilia, primary
  • Prothrombin Gene Mutater
  • Factor V Leiden (APC resistance)
  • Deficiency, deficient, protein, C
  • Deficiency, deficient, protein, S
  • Inherited, hypercoagulable states
  • Hypercoagulable states (Inherited)
  • Deficiency, deficient, antithrombin, antithrombin III
  • Mutation, prothrombin gene [factor V Leiden mutation]
  • Resistance, resistant (to), activated protein C [factor V Leiden mutation]

Notes for D68.5

As CIHI prints them, with any note D68.5 takes from the headings above it.

Includes

  • Activated protein C resistance [factor V Leiden mutation]Deficiency:• antithrombin, antithrombin III• protein C• protein SProthrombin gene mutation

Excludes

Conditions classified elsewhere.

  • Those complicating:• abortion or ectopic or molar pregnancy (O00-O07) (O08.1)• pregnancy, childbirth and the puerperium (O45.-)(O46.-)(O67.-)(O72.3-)From D68 Other coagulation defects
  • Autoimmune disease (systemic) NOS (M35.9)certain conditions originating in the perinatal period (P00-P96)complications of pregnancy, childbirth and the puerperium (O00-O99)congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)endocrine, nutritional and metabolic diseases (E00-E90)human immunodeficiency virus [HIV] disease (B24)injury, poisoning and certain other consequences of external causes (S00-T98)neoplasms (C00-D48)symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)From Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Where D68.5 sits

  1. 1ChapterChapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
  2. 2Block D65-D69Coagulation defects, purpura and other haemorrhagic conditions
  3. 3Category D68Other coagulation defects
  4. 4Valid code D68.5Primary thrombophilia

Source and release

Data release
ICD-10-CA · FY 2026–2027
Effective date
Apr 1, 2026
Publisher
CIHI

This page is built from the ICD-10-CA catalog that Vero Codes reads when it suggests codes: Canadian Institute for Health Information’s FY 2026–2027 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

See D68.5 in the CIHI source

Frequently asked questions

What does ICD-10-CA code D68.5 mean?

D68.5 is the ICD-10-CA code for “Primary thrombophilia” in CIHI’s ICD-10-CA FY 2026–2027 release.

Where is D68.5 in ICD-10-CA?

D68.5 sits under D68 Other coagulation defects, within D65-D69 Coagulation defects, purpura and other haemorrhagic conditions, within Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).

What coding notes apply to D68.5?

ICD-10-CA lists Includes, Excludes notes for D68.5, including those from the headings it sits under. They are listed on this page with where each one comes from.

Which ICD-10-CA release does this page use?

It uses CIHI’s FY 2026–2027 release, in effect from Apr 1, 2026 to Mar 31, 2027. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.

Codes beside D68.5

D68.0Von Willebrand's diseaseD68.1Hereditary factor XI deficiencyD68.2Hereditary deficiency of other clotting factorsD68.3Haemorrhagic disorder due to circulating anticoagulantsD68.4Acquired coagulation factor deficiencyD68.6Other thrombophiliaD68.8Other specified coagulation defectsD68.9Coagulation defect, unspecified