U0005 HCPCS Level II code: Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19])…

CMS terminated U0005: its last date of service was May 11, 2023. It stays here for looking up older claims; newer services need a current code.

Official description

U0005

Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc, making use of high throughput technologies, completed within 2 calendar days from date of specimen collection (list separately in addition to either hcpcs code u0003 or u0004) as described by cms-2020-01-r2

Short description: Infec agen detec ampli probe

HCPCS · United States

Medicare details

The indicators CMS publishes with U0005 in its October 2026 file. They describe Medicare’s handling, not another payer’s.

Medicare coverage
Carrier judgment
Medicare pricing
Clinical lab fee schedule – Price established by carriers (e.g., gap-fills, carrier established panels)
Type of service
Diagnostic laboratory
BETOS category
Lab tests - other (Non-Medicare fee schedule)
Added
Jan 1, 2021
Terminated after
May 11, 2023

Where U0005 sits

  1. 1U codesLaboratory testing (special program codes)
  2. 2Terminated U0005Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, cdc or non-cdc, making use of high throughput technologies, completed within 2 calendar days from date of specimen collection (list separately in addition to either hcpcs code u0003 or u0004) as described by cms-2020-01-r2

Source and release

Data release
HCPCS Level II · October 2026
Effective date
Oct 1, 2026
Publisher
CMS

This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

Frequently asked questions

Is HCPCS code U0005 still valid?

No. CMS terminated U0005; its last date of service was May 11, 2023. It is listed for looking up services from before then. Use a current code for newer services.

Does Medicare cover U0005?

CMS lists U0005’s Medicare coverage as “Carrier judgment” and its pricing as “Clinical lab fee schedule – Price established by carriers (e.g., gap-fills, carrier established panels)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.

Which HCPCS Level II release does this page use?

It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.