S3721 HCPCS Level II code: Prostate cancer antigen 3 (pca3) testing
CMS terminated S3721: its last date of service was Dec 31, 2015. It stays here for looking up older claims; newer services need a current code.
Official description
S3721Prostate cancer antigen 3 (pca3) testing
Short description: Pca3 testing
HCPCS · United States
Medicare details
The indicators CMS publishes with S3721 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Not payable by Medicare
- Medicare pricing
- Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)
- Type of service
- Other medical items or services
- BETOS category
- Undefined codes
- Added
- Apr 1, 2012
- Terminated after
- Dec 31, 2015
Where S3721 sits
- 1S codesTemporary national codes (non-Medicare)
- 2Terminated S3721Prostate cancer antigen 3 (pca3) testing
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
Is HCPCS code S3721 still valid?
No. CMS terminated S3721; its last date of service was Dec 31, 2015. It is listed for looking up services from before then. Use a current code for newer services.
Does Medicare cover S3721?
CMS lists S3721’s Medicare coverage as “Not payable by Medicare” and its pricing as “Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside S3721
All S codesS3630Eosinophil count, blood, directS3645Hiv-1 antibody testing of oral mucosal transudateS3650Saliva test, hormone level; during menopauseS3652Saliva test, hormone level; to assess preterm labor riskS3655Antisperm antibodies test (immunobead)S3708Gastrointestinal fat absorption studyS3722Dose optimization by area under the curve (auc) analysis, for infusional 5-fluorouracilS3800Genetic testing for amyotrophic lateral sclerosis (als)S3840Dna analysis for germline mutations of the ret proto-oncogene for susceptibility to multiple endocrine neoplasia type 2S3841Genetic testing for retinoblastomaS3842Genetic testing for von hippel-lindau diseaseS3844Dna analysis of the connexin 26 gene (gjb2) for susceptibility to congenital, profound deafness