S0021 HCPCS Level II code: Injection, cefoperazone sodium, 1 gram
S0021 is the HCPCS code for “Injection, cefoperazone sodium, 1 gram” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
S0021Injection, cefoperazone sodium, 1 gram
Short description: Injection, cefoperazone sod
HCPCS · United States
Notes for S0021
As CMS prints them, with any note S0021 takes from the headings above it.
Note
- CMS processing note 0088: "S" CODES ARE UNIQUE TEMPORARY CODES ESTABLISHED BY BCBSA AND HIAA FOR PRIVATE PAYOR USE. THEY ARE NOT VALID NOR PAYABLE BY MEDICARE.
Medicare details
The indicators CMS publishes with S0021 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Not payable by Medicare
- Medicare pricing
- Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)
- Type of service
- Medical care; Lump sum purchase of DME, prosthetics, orthotics
- BETOS category
- Undefined codes
- Added
- Jan 1, 2000
Where S0021 sits
- 1S codesTemporary national codes (non-Medicare)
- 2Active code S0021Injection, cefoperazone sodium, 1 gram
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code S0021 mean?
S0021 is the HCPCS code for “Injection, cefoperazone sodium, 1 gram” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover S0021?
CMS lists S0021’s Medicare coverage as “Not payable by Medicare” and its pricing as “Service not separately priced by Part B (e.g., services not covered, bundled, used by Part A only, etc.)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside S0021
All S codesS0012Butorphanol tartrate, nasal spray, 25 mgS0013Esketamine, nasal spray, 1 mgS0014Tacrine hydrochloride, 10 mgS0017Injection, aminocaproic acid, 5 gramsS0020Injection, bupivicaine hydrochloride, 30 mlS0023Injection, cimetidine hydrochloride, 300 mgS0028Injection, famotidine, 20 mgS0030Injection, metronidazole, 500 mgS0032Injection, nafcillin sodium, 2 gramsS0034Injection, ofloxacin, 400 mgS0039Injection, sulfamethoxazole and trimethoprim, 10 ml