Q5159 HCPCS Level II code: Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
Q5159 is the HCPCS code for “Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
Q5159Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
Short description: Inj, denosumab-dssb, 1 mg
HCPCS · United States
Medicare details
The indicators CMS publishes with Q5159 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Carrier judgment
- Medicare pricing
- Drugs
- Type of service
- Medical care
- BETOS category
- Chemotherapy
- Added
- Oct 1, 2025
Where Q5159 sits
- 1Q codesTemporary codes
- 2Active code Q5159Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code Q5159 mean?
Q5159 is the HCPCS code for “Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover Q5159?
CMS lists Q5159’s Medicare coverage as “Carrier judgment” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside Q5159
All Q codesQ5153Injection, aflibercept-yszy (opuviz), biosimilar, 1 mgQ5154Injection, omalizumab-igec (omlyclo), biosimilar, 5 mgQ5155Injection, aflibercept-jbvf (yesafili), biosimilar, 1 mgQ5156Injection, tocilizumab-anoh (avtozma), biosimilar, 1 mgQ5157Injection, denosumab-bmwo (stoboclo/osenvelt), biosimilar, 1 mgQ5158Injection, denosumab-bnht (bomyntra/conexxence), biosimilar, 1 mgQ5160Injection, bevacizumab-nwgd (jobevne), biosimilar, 10 mgQ5161Injection, denosumab-kyqq (aukelso/bosaya), biosimilar, 1 mgQ5162Injection, denosumab-nxxp (bildyos/bilprevda), biosimilar, 1 mgQ5164Injection, ustekinumab-hmny (starjemza), biosimilar, 1 mgQ5165Injection, denosumab-mobz (oziltus), biosimilar, 1 mgQ5166Injection, denosumab-desu (osvyrti/jubereq), biosimilar, 1 mg