Q4255 HCPCS Level II code: Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)

Q4255 is the HCPCS code for “Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)” in CMS’s October 2026 release, in effect from Oct 1, 2026.

Official description

Q4255

Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)

Short description: Reguard, topical use per sq

HCPCS · United States

Medicare details

The indicators CMS publishes with Q4255 in its October 2026 file. They describe Medicare’s handling, not another payer’s.

Medicare coverage: Carrier judgment
Medicare pricing: Physician fee schedule – Price established using national RVUs
ASC: Approved for ambulatory surgical centers
Type of service: Medical care
BETOS category: Other drugs
Added: Oct 1, 2020

Where Q4255 sits

1Q codesTemporary codes
2Active code Q4255Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)

Source and release

Data release: HCPCS Level II · October 2026
Effective date: Oct 1, 2026
Publisher: CMS

This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.

See Q4255 in the CMS source

Frequently asked questions

What does HCPCS code Q4255 mean?

Q4255 is the HCPCS code for “Reguard, for topical use only, per square centimeter (add-on, list separately in addition to primary procedure)” in CMS’s HCPCS Level II October 2026 release.

Does Medicare cover Q4255?

CMS lists Q4255’s Medicare coverage as “Carrier judgment” and its pricing as “Physician fee schedule – Price established using national RVUs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.

Which HCPCS Level II release does this page use?

It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.

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