Q4100 HCPCS Level II code: Skin substitute, not otherwise specified
CMS terminated Q4100: its last date of service was Dec 31, 2025. It stays here for looking up older claims; newer services need a current code.
Official description
Q4100Skin substitute, not otherwise specified
Short description: Skin substitute, nos
HCPCS · United States
Medicare details
The indicators CMS publishes with Q4100 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Carrier judgment
- Medicare pricing
- Drugs
- Type of service
- Medical care
- BETOS category
- Other drugs
- Added
- Jan 1, 2009
- Terminated after
- Dec 31, 2025
Where Q4100 sits
- 1Q codesTemporary codes
- 2Terminated Q4100Skin substitute, not otherwise specified
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
Is HCPCS code Q4100 still valid?
No. CMS terminated Q4100; its last date of service was Dec 31, 2025. It is listed for looking up services from before then. Use a current code for newer services.
Does Medicare cover Q4100?
CMS lists Q4100’s Medicare coverage as “Carrier judgment” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside Q4100
All Q codesQ4049Finger splint, staticQ4050Cast supplies, for unlisted types and materials of castsQ4051Splint supplies, miscellaneous (includes thermoplastics, strapping, fasteners, padding and other supplies)Q4074Iloprost, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, up to 20 microgramsQ4081Injection, epoetin alfa, 100 units (for esrd on dialysis)Q4082Drug or biological, not otherwise classified, part b drug competitive acquisition program (cap)Q4101Apligraf, per square centimeter (add-on, list separately in addition to primary procedure)Q4102Oasis wound matrix, per square centimeter (add-on, list separately in addition to primary procedure)Q4103Oasis burn matrix, per square centimeter (add-on, list separately in addition to primary procedure)Q4104Integra bilayer matrix wound dressing (bmwd), per square centimeter (add-on, list separately in addition to primary procedure)Q4105Integra dermal regeneration template (drt) or integra omnigraft dermal regeneration matrix, per square centimeter (add-on, list separately in addition to primary procedure)Q4106Dermagraft, per square centimeter