J8612 HCPCS Level II code: Methotrexate (xatmep), oral, 2.5 mg
J8612 is the HCPCS code for “Methotrexate (xatmep), oral, 2.5 mg” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
J8612Methotrexate (xatmep), oral, 2.5 mg
Short description: Oral methotrexate (xatmep)
HCPCS · United States
Medicare details
The indicators CMS publishes with J8612 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Special coverage instructions apply
- Medicare pricing
- Drugs
- ASC
- Approved for ambulatory surgical centers
- Type of service
- Medical care; Immunosuppressive drugs; Lump sum purchase of DME, prosthetics, orthotics
- BETOS category
- Chemotherapy
- Added
- Jul 1, 2024
Where J8612 sits
- 1J codesDrugs administered other than orally
- 2Active code J8612Methotrexate (xatmep), oral, 2.5 mg
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code J8612 mean?
J8612 is the HCPCS code for “Methotrexate (xatmep), oral, 2.5 mg” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover J8612?
CMS lists J8612’s Medicare coverage as “Special coverage instructions apply” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside J8612
All J codesJ8562Fludarabine phosphate, oral, 10 mgJ8565Gefitinib, oral, 250 mgJ8597Antiemetic drug, oral, not otherwise specifiedJ8600Melphalan; oral, 2 mgJ8610Methotrexate; oral, 2.5 mgJ8611Methotrexate (jylamvo), oral, 2.5 mgJ8650Nabilone, oral, 1 mgJ8655Netupitant 300 mg and palonosetron 0.5 mg, oralJ8670Rolapitant, oral, 1 mgJ8700Temozolomide, oral, 5 mgJ8705Topotecan, oral, 0.25 mgJ8999Prescription drug, oral, chemotherapeutic, nos