J2251 HCPCS Level II code: Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg
J2251 is the HCPCS code for “Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
J2251Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg
Short description: Inj midazolam in 0.9% nacl
HCPCS · United States
Medicare details
The indicators CMS publishes with J2251 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Special coverage instructions apply
- Medicare pricing
- Drugs
- Type of service
- Medical care; Lump sum purchase of DME, prosthetics, orthotics
- BETOS category
- Other drugs
- Added
- Jan 1, 2023
Where J2251 sits
- 1J codesDrugs administered other than orally
- 2Active code J2251Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code J2251 mean?
J2251 is the HCPCS code for “Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover J2251?
CMS lists J2251’s Medicare coverage as “Special coverage instructions apply” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside J2251
All J codesJ2212Injection, methylnaltrexone, 0.1 mgJ2246Injection, micafungin in sodium (baxter), not therapeutically equivalent to j2248, 1 mgJ2247Injection, micafungin sodium (par pharm) not thereapeutically equivalent to j2248, 1 mgJ2248Injection, micafungin sodium, 1 mgJ2249Injection, remimazolam, 1 mgJ2250Injection, midazolam hydrochloride, per 1 mgJ2252Injection, midazolam in 0.8% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mgJ2253Injection, midazolam (seizalam), 1 mgJ2260Injection, milrinone lactate, 5 mgJ2265Injection, minocycline hydrochloride, 1 mgJ2267Injection, mirikizumab-mrkz, 1 mgJ2270Injection, morphine sulfate, up to 10 mg