J0641 HCPCS Level II code: Injection, levoleucovorin, not otherwise specified, 0.5 mg
J0641 is the HCPCS code for “Injection, levoleucovorin, not otherwise specified, 0.5 mg” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
J0641Injection, levoleucovorin, not otherwise specified, 0.5 mg
Short description: Inj levoleucovorin nos 0.5mg
HCPCS · United States
Notes for J0641
As CMS prints them, with any note J0641 takes from the headings above it.
Note
- CMS processing note 0127: PUBLICATION 100.2, CHAPTER 15, 50.1.
Medicare details
The indicators CMS publishes with J0641 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Special coverage instructions apply
- Medicare pricing
- Drugs
- ASC
- Approved for ambulatory surgical centers
- Type of service
- Medical care; Lump sum purchase of DME, prosthetics, orthotics
- BETOS category
- Other drugs
- Added
- Jan 1, 2009
Where J0641 sits
- 1J codesDrugs administered other than orally
- 2Active code J0641Injection, levoleucovorin, not otherwise specified, 0.5 mg
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code J0641 mean?
J0641 is the HCPCS code for “Injection, levoleucovorin, not otherwise specified, 0.5 mg” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover J0641?
CMS lists J0641’s Medicare coverage as “Special coverage instructions apply” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside J0641
All J codesJ0620Injection, calcium glycerophosphate and calcium lactate, per 10 mlJ0630Injection, calcitonin salmon, up to 400 unitsJ0636Injection, calcitriol, 0.1 mcgJ0637Injection, caspofungin acetate, 5 mgJ0638Injection, canakinumab, 1 mgJ0640Injection, leucovorin calcium, per 50 mgJ0642Injection, levoleucovorin (khapzory), 0.5 mgJ0643Injection, leucovorin calcium, not otherwise specified, 1 mgJ0644Injection, leucovorin calcium (avyxa), 1 mgJ0650Injection, levothyroxine sodium, not otherwise specified, 10 mcgJ0651Injection, levothyroxine sodium (fresenius kabi), not therapeutically equivalent to j0650, 10 mcgJ0652Injection, levothyroxine sodium (hikma), not therapeutically equivalent to j0650, 10 mcg