J0578 HCPCS Level II code: Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy
J0578 is the HCPCS code for “Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
J0578Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy
Short description: Inj brixadi, more than 7 day
HCPCS · United States
Medicare details
The indicators CMS publishes with J0578 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Carrier judgment
- Medicare pricing
- Drugs
- ASC
- Approved for ambulatory surgical centers
- Type of service
- Medical care
- BETOS category
- Other drugs
- Added
- Apr 1, 2024
Where J0578 sits
- 1J codesDrugs administered other than orally
- 2Active code J0578Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code J0578 mean?
J0578 is the HCPCS code for “Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover J0578?
CMS lists J0578’s Medicare coverage as “Carrier judgment” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside J0578
All J codesJ0572Buprenorphine/naloxone, oral, less than or equal to 3 mg buprenorphineJ0573Buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphineJ0574Buprenorphine/naloxone, oral, greater than 6 mg, but less than or equal to 10 mg buprenorphineJ0575Buprenorphine/naloxone, oral, greater than 10 mg buprenorphineJ0576Injection, buprenorphine extended-release (brixadi), 1 mgJ0577Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapyJ0582Injection, bivalirudin (endo), not therapeutically equivalent to j0583, 1 mgJ0583Injection, bivalirudin, 1 mgJ0584Injection, burosumab-twza 1 mgJ0585Injection, onabotulinumtoxina, 1 unitJ0586Injection, abobotulinumtoxina, 5 unitsJ0587Injection, rimabotulinumtoxinb, 100 units