J0270 HCPCS Level II code: Injection, alprostadil, 1.25 mcg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is…
J0270 is the HCPCS code for “Injection, alprostadil, 1.25 mcg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
J0270Injection, alprostadil, 1.25 mcg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
Short description: Alprostadil for injection
HCPCS · United States
Medicare details
The indicators CMS publishes with J0270 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Special coverage instructions apply
- Medicare pricing
- Drugs
- Type of service
- Medical care
- BETOS category
- Other drugs
- Added
- Jan 1, 1997
Where J0270 sits
- 1J codesDrugs administered other than orally
- 2Active code J0270Injection, alprostadil, 1.25 mcg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code J0270 mean?
J0270 is the HCPCS code for “Injection, alprostadil, 1.25 mcg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover J0270?
CMS lists J0270’s Medicare coverage as “Special coverage instructions apply” and its pricing as “Drugs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside J0270
All J codesJ0223Injection, givosiran, 0.5 mgJ0224Injection, lumasiran, 0.5 mgJ0225Injection, vutrisiran, 1 mgJ0248Injection, remdesivir, 1 mgJ0256Injection, alpha 1 proteinase inhibitor (human), not otherwise specified, 10 mgJ0257Injection, alpha 1 proteinase inhibitor (human), (glassia), 10 mgJ0275Alprostadil urethral suppository (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)J0278Injection, amikacin sulfate, 100 mgJ0280Injection, aminophyllin, up to 250 mgJ0281Injection, aminocaproic acid, 1 gramJ0282Injection, amiodarone hydrochloride, 30 mgJ0283Injection, amiodarone hydrochloride (nexterone), 30 mg