G0121 HCPCS Level II code: Colorectal cancer screening; colonoscopy on individual not meeting criteria for high risk
G0121 is the HCPCS code for “Colorectal cancer screening; colonoscopy on individual not meeting criteria for high risk” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
G0121Colorectal cancer screening; colonoscopy on individual not meeting criteria for high risk
Short description: Colon ca scrn not hi rsk ind
HCPCS · United States
Notes for G0121
As CMS prints them, with any note G0121 takes from the headings above it.
Note
- CMS processing note 0064: COVERAGE AND PAYMENT BASED ON BALANCED BUDGET ACT OF 1997 (G0101 - SEC 4102; G0104, G0105, G0106, G0107, G0120, G0121, G0122, G0128 - SEC 4104).
Medicare details
The indicators CMS publishes with G0121 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Special coverage instructions apply
- Medicare pricing
- Physician fee schedule – Price established using national RVUs
- ASC
- Approved for ambulatory surgical centers
- Type of service
- Surgery
- BETOS category
- Endoscopy - colonoscopy
- Added
- Jan 1, 1998
Where G0121 sits
- 1G codesProcedures and professional services
- 2Active code G0121Colorectal cancer screening; colonoscopy on individual not meeting criteria for high risk
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code G0121 mean?
G0121 is the HCPCS code for “Colorectal cancer screening; colonoscopy on individual not meeting criteria for high risk” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover G0121?
CMS lists G0121’s Medicare coverage as “Special coverage instructions apply” and its pricing as “Physician fee schedule – Price established using national RVUs”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside G0121
All G codesG0106Colorectal cancer screening; alternative to g0104, screening sigmoidoscopy, barium enemaG0108Diabetes outpatient self-management training services, individual, per 30 minutesG0109Diabetes outpatient self-management training services, group session (2 or more), per 30 minutesG0117Glaucoma screening for high risk patients furnished by an optometrist or ophthalmologistG0118Glaucoma screening for high risk patient furnished under the direct supervision of an optometrist or ophthalmologistG0120Colorectal cancer screening; alternative to g0105, screening colonoscopy, barium enema.G0122Colorectal cancer screening; barium enemaG0123Screening cytopathology, cervical or vaginal (any reporting system), collected in preservative fluid, automated thin layer preparation, screening by cytotechnologist under…G0124Screening cytopathology, cervical or vaginal (any reporting system), collected in preservative fluid, automated thin layer preparation, requiring interpretation by physicianG0127Trimming of dystrophic nails, any numberG0128Direct (face-to-face with patient) skilled nursing services of a registered nurse provided in a comprehensive outpatient rehabilitation facility, each 10 minutes beyond the first…G0129Occupational therapy services requiring the skills of a qualified occupational therapist, furnished as a component of a partial hospitalization or intensive outpatient treatment…