A4321 HCPCS Level II code: Therapeutic agent for urinary catheter irrigation
A4321 is the HCPCS code for “Therapeutic agent for urinary catheter irrigation” in CMS’s October 2026 release, in effect from Oct 1, 2026.
Official description
A4321Therapeutic agent for urinary catheter irrigation
Short description: Cath therapeutic irrig agent
HCPCS · United States
Medicare details
The indicators CMS publishes with A4321 in its October 2026 file. They describe Medicare’s handling, not another payer’s.
- Medicare coverage
- Special coverage instructions apply
- Medicare pricing
- DMEPOS fee schedule – Ostomy, tracheostomy and urological supplies (price subject to floors and ceilings)
- Type of service
- Lump sum purchase of DME, prosthetics, orthotics
- BETOS category
- Prosthetic/Orthotic devices
- Added
- Jan 1, 1997
Where A4321 sits
- 1A codesAmbulance, supplies and miscellaneous
- 2Active code A4321Therapeutic agent for urinary catheter irrigation
Source and release
- Data release
- HCPCS Level II · October 2026
- Effective date
- Oct 1, 2026
- Publisher
- CMS
This page is built from the HCPCS Level II catalog that Vero Codes reads when it suggests codes: Centers for Medicare & Medicaid Services’s October 2026 release, imported from the publisher’s file and checked against it. The description, notes and structured data come from the same record.
Frequently asked questions
What does HCPCS code A4321 mean?
A4321 is the HCPCS code for “Therapeutic agent for urinary catheter irrigation” in CMS’s HCPCS Level II October 2026 release.
Does Medicare cover A4321?
CMS lists A4321’s Medicare coverage as “Special coverage instructions apply” and its pricing as “DMEPOS fee schedule – Ostomy, tracheostomy and urological supplies (price subject to floors and ceilings)”. Coverage and payment still depend on the patient, the setting, the documentation and the payer.
Which HCPCS Level II release does this page use?
It uses CMS’s October 2026 release, in effect from Oct 1, 2026 to Dec 31, 2026. It is a reference: confirm the code against the current list and the payer’s rules before you submit it.
Codes beside A4321
All A codesA4313Insertion tray without drainage bag with indwelling catheter, foley type, three-way, for continuous irrigationA4314Insertion tray with drainage bag with indwelling catheter, foley type, two-way latex with coating (teflon, silicone, silicone elastomer or hydrophilic, etc.)A4315Insertion tray with drainage bag with indwelling catheter, foley type, two-way, all siliconeA4316Insertion tray with drainage bag with indwelling catheter, foley type, three-way, for continuous irrigationA4318Female external urinary collection cup, with or without ring attachment, per dayA4320Irrigation tray with bulb or piston syringe, any purposeA4322Irrigation syringe, bulb or piston, eachA4326Male external catheter with integral collection chamber, any type, eachA4327Female external urinary collection device; meatal cup, eachA4328Female external urinary collection device; pouch, eachA4330Perianal fecal collection pouch with adhesive, eachA4331Extension drainage tubing, any type, any length, with connector/adaptor, for use with urinary leg bag or urostomy pouch, each