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U.S. ICD-10-CM · FY 2027

E78.010 ICD-10-CM Code: Homozygous familial hypercholesterolemia [HoFH]

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

E78.010

Homozygous familial hypercholesterolemia [HoFH]

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where E78.010 sits

  1. 1

    Chapter 4

    Endocrine, nutritional and metabolic diseases (E00-E89)

  2. 2

    Section

    Metabolic disorders (E70-E88)

  3. 3

    Category E78

    Disorders of lipoprotein metabolism and other lipidemias

  4. 4

    Subcategory E78.01

    Familial hypercholesterolemia

  5. 5

    Code E78.010

    Homozygous familial hypercholesterolemia [HoFH]

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for E78.010.

Code first

No “code first” instruction is listed for E78.010.

Use additional code

No “use additional code” instruction is listed for E78.010.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for E78.010.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for E78.010.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code E78.010 mean?

E78.010 is the FY 2027 U.S. ICD-10-CM code for “Homozygous familial hypercholesterolemia [HoFH].”

Is E78.010 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, E78.010 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is E78.010 located in ICD-10-CM?

E78.010 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Metabolic disorders (E70-E88) (E70–E88), under category E78, Disorders of lipoprotein metabolism and other lipidemias and subcategory E78.01, Familial hypercholesterolemia.

What coding notes are listed for E78.010?

No inclusion terms are listed for E78.010 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.

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