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U.S. ICD-10-CM · FY 2027

Z16.12 ICD-10-CM Code: Extended spectrum beta lactamase (ESBL) resistance

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

Z16.12

Extended spectrum beta lactamase (ESBL) resistance

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where Z16.12 sits

  1. 1

    Chapter 21

    Factors influencing health status and contact with health services (Z00-Z99)

  2. 2

    Section

    Resistance to antimicrobial drugs (Z16)

  3. 3

    Category Z16

    Resistance to antimicrobial drugs

  4. 4

    Subcategory Z16.1

    Resistance to beta lactam antibiotics

  5. 5

    Code Z16.12

    Extended spectrum beta lactamase (ESBL) resistance

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for Z16.12.

Code first

No “code first” instruction is listed for Z16.12.

Use additional code

No “use additional code” instruction is listed for Z16.12.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for Z16.12.

Excludes2

Conditions not included here that may be reported separately when present.

  • Methicillin resistant Staphylococcus aureus infection in diseases classified elsewhere (B95.62)

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code Z16.12 mean?

Z16.12 is the FY 2027 U.S. ICD-10-CM code for “Extended spectrum beta lactamase (ESBL) resistance.”

Is Z16.12 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, Z16.12 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is Z16.12 located in ICD-10-CM?

Z16.12 is listed in Chapter 21, Factors influencing health status and contact with health services (Z00-Z99), within Resistance to antimicrobial drugs (Z16) (Z16–Z16), under category Z16, Resistance to antimicrobial drugs and subcategory Z16.1, Resistance to beta lactam antibiotics.

What coding notes are listed for Z16.12?

No inclusion terms are listed for Z16.12 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. Excludes2 notes: Methicillin resistant Staphylococcus aureus infection in diseases classified elsewhere (B95.62).

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