U.S. ICD-10-CM · FY 2027

G12.21 ICD-10-CM Code: Amyotrophic lateral sclerosis

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

G12.21

Amyotrophic lateral sclerosis

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where G12.21 sits

  1. 1

    Chapter 6

    Diseases of the nervous system (G00-G99)

  2. 2

    Section

    Systemic atrophies primarily affecting the central nervous system (G10-G14)

  3. 3

    Category G12

    Spinal muscular atrophy and related syndromes

  4. 4

    Subcategory G12.2

    Motor neuron disease

  5. 5

    Code G12.21

    Amyotrophic lateral sclerosis

Documentation details

Notes for this code

Inclusion terms

No inclusion terms are listed for G12.21.

Code first

No “code first” instruction is listed for G12.21.

Use additional code

No “use additional code” instruction is listed for G12.21.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for G12.21.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for G12.21.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code G12.21 mean?

G12.21 is the FY 2027 U.S. ICD-10-CM code for “Amyotrophic lateral sclerosis.”

Is G12.21 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, G12.21 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is G12.21 located in ICD-10-CM?

G12.21 is listed in Chapter 6, Diseases of the nervous system (G00-G99), within Systemic atrophies primarily affecting the central nervous system (G10-G14) (G10–G14), under category G12, Spinal muscular atrophy and related syndromes and subcategory G12.2, Motor neuron disease.

What coding notes are listed for G12.21?

No inclusion terms are listed for G12.21 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.

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