F45.21 ICD-10-CM Code: Hypochondriasis

F45.21 is the billable ICD-10-CM code for “Hypochondriasis” in the FY 2027 U.S. code set, effective Oct 1, 2026.

Official description

F45.21

Hypochondriasis

ICD-10-CM diagnosis code · United States clinical modification

Where F45.21 sits

  1. 1

    Chapter 5

    Mental, Behavioral and Neurodevelopmental disorders (F01-F99)

  2. 2

    Section

    Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders (F40-F48)

  3. 3

    Category F45

    Somatoform disorders

  4. 4

    Subcategory F45.2

    Hypochondriacal disorders

  5. 5

    Code F45.21

    Hypochondriasis

Notes for this code

Inclusion terms

  • Hypochondriacal neurosis
  • Illness anxiety disorder

Code first

No “code first” instruction is listed for F45.21.

Use additional code

No “use additional code” instruction is listed for F45.21.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for F45.21.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for F45.21.

Source and release

Data release
U.S. ICD-10-CM · FY 2027
Effective date
Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Frequently asked questions

What does ICD-10-CM code F45.21 mean?

F45.21 is the FY 2027 U.S. ICD-10-CM code for “Hypochondriasis.”

Is F45.21 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, F45.21 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is F45.21 located in ICD-10-CM?

F45.21 is listed in Chapter 5, Mental, Behavioral and Neurodevelopmental disorders (F01-F99), within Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders (F40-F48) (F40–F48), under category F45, Somatoform disorders and subcategory F45.2, Hypochondriacal disorders.

What coding notes are listed for F45.21?

Its listed inclusion terms are Hypochondriacal neurosis; Illness anxiety disorder. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.