E88.81 ICD-10-CM Code: Metabolic syndrome and other insulin resistance
A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.
Official description
E88.81Metabolic syndrome and other insulin resistance
ICD-10-CM diagnosis code · United States clinical modification
Where E88.81 sits
- 1
Chapter 4
Endocrine, nutritional and metabolic diseases (E00-E89)
- 2
Section
Metabolic disorders (E70-E88)
- 3
Category E88
Other and unspecified metabolic disorders
- 4
Subcategory E88.8
Other specified metabolic disorders
- 5
Code E88.81
Metabolic syndrome and other insulin resistance
Codes under E88.81
E88.81 is a non-billable category. Choose the child code that best matches the documented diagnosis.
Notes for this code
Inclusion terms
No inclusion terms are listed for E88.81.
Code first
No “code first” instruction is listed for E88.81.
Use additional code
- codes for associated manifestations, such as:
- obesity (E66.-)
Excludes1
Conditions that should not be reported together with this code.
No Excludes1 note is listed for E88.81.
Excludes2
Conditions not included here that may be reported separately when present.
No Excludes2 note is listed for E88.81.
Source and release
- Data release
- U.S. ICD-10-CM · FY 2027
- Effective date
- Oct 1, 2026
- Publisher
- Vero Scribe Inc.
This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.
Frequently asked questions
What does ICD-10-CM code E88.81 mean?
E88.81 is the FY 2027 U.S. ICD-10-CM code for “Metabolic syndrome and other insulin resistance.”
Is E88.81 a billable or specific ICD-10-CM code?
No. E88.81 has more specific child codes in the FY 2027 reference data. Select the code that matches the documentation and confirm the active code set and payer requirements.
Where is E88.81 located in ICD-10-CM?
E88.81 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Metabolic disorders (E70-E88) (E70–E88), under category E88, Other and unspecified metabolic disorders and subcategory E88.8, Other specified metabolic disorders.
What coding notes are listed for E88.81?
No inclusion terms are listed for E88.81 in this reference record. No code-first instruction is listed. Additional-code instructions: codes for associated manifestations, such as:; obesity (E66.-). No Excludes1 note is listed. No Excludes2 note is listed.