E78.72 ICD-10-CM Code: Smith-Lemli-Opitz syndrome

E78.72 is the billable ICD-10-CM code for “Smith-Lemli-Opitz syndrome” in the FY 2027 U.S. code set, effective Oct 1, 2026.

Official description

E78.72

Smith-Lemli-Opitz syndrome

ICD-10-CM diagnosis code · United States clinical modification

Where E78.72 sits

  1. 1

    Chapter 4

    Endocrine, nutritional and metabolic diseases (E00-E89)

  2. 2

    Section

    Metabolic disorders (E70-E88)

  3. 3

    Category E78

    Disorders of lipoprotein metabolism and other lipidemias

  4. 4

    Subcategory E78.7

    Disorders of bile acid and cholesterol metabolism

  5. 5

    Code E78.72

    Smith-Lemli-Opitz syndrome

Notes for this code

Inclusion terms

No inclusion terms are listed for E78.72.

Code first

No “code first” instruction is listed for E78.72.

Use additional code

No “use additional code” instruction is listed for E78.72.

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for E78.72.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for E78.72.

Source and release

Data release
U.S. ICD-10-CM · FY 2027
Effective date
Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Frequently asked questions

What does ICD-10-CM code E78.72 mean?

E78.72 is the FY 2027 U.S. ICD-10-CM code for “Smith-Lemli-Opitz syndrome.”

Is E78.72 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, E78.72 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is E78.72 located in ICD-10-CM?

E78.72 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Metabolic disorders (E70-E88) (E70–E88), under category E78, Disorders of lipoprotein metabolism and other lipidemias and subcategory E78.7, Disorders of bile acid and cholesterol metabolism.

What coding notes are listed for E78.72?

No inclusion terms are listed for E78.72 in this reference record. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.