U.S. ICD-10-CM · FY 2027

E78.2 ICD-10-CM Code: Mixed hyperlipidemia

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

E78.2

Mixed hyperlipidemia

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where E78.2 sits

  1. 1

    Chapter 4

    Endocrine, nutritional and metabolic diseases (E00-E89)

  2. 2

    Section

    Metabolic disorders (E70-E88)

  3. 3

    Category E78

    Disorders of lipoprotein metabolism and other lipidemias

  4. 4

    Code E78.2

    Mixed hyperlipidemia

Documentation details

Notes for this code

Inclusion terms

  • Broad- or floating-betalipoproteinemia
  • Combined hyperlipidemia NOS
  • Elevated cholesterol with elevated triglycerides NEC
  • Fredrickson's hyperlipoproteinemia, type IIb or III
  • Hyperbetalipoproteinemia with prebetalipoproteinemia
  • Hypercholesteremia with endogenous hyperglyceridemia
  • Hyperlipidemia, group C
  • Tubo-eruptive xanthoma
  • Xanthoma tuberosum

Code first

No “code first” instruction is listed for E78.2.

Use additional code

No “use additional code” instruction is listed for E78.2.

Excludes1

Conditions that should not be reported together with this code.

  • cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5)
  • familial combined hyperlipidemia (E78.49)

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for E78.2.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code E78.2 mean?

E78.2 is the FY 2027 U.S. ICD-10-CM code for “Mixed hyperlipidemia.”

Is E78.2 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, E78.2 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is E78.2 located in ICD-10-CM?

E78.2 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Metabolic disorders (E70-E88) (E70–E88), under category E78, Disorders of lipoprotein metabolism and other lipidemias.

What coding notes are listed for E78.2?

Its listed inclusion terms are Broad- or floating-betalipoproteinemia; Combined hyperlipidemia NOS; Elevated cholesterol with elevated triglycerides NEC; Fredrickson's hyperlipoproteinemia, type IIb or III; Hyperbetalipoproteinemia with prebetalipoproteinemia; Hypercholesteremia with endogenous hyperglyceridemia; Hyperlipidemia, group C; Tubo-eruptive xanthoma; Xanthoma tuberosum. No code-first instruction is listed. Excludes1 notes: cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5); familial combined hyperlipidemia (E78.49). No Excludes2 note is listed.

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