E16.4 ICD-10-CM Code: Increased secretion of gastrin
A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.
Official description
E16.4Increased secretion of gastrin
ICD-10-CM diagnosis code · United States clinical modification
Where E16.4 sits
- 1
Chapter 4
Endocrine, nutritional and metabolic diseases (E00-E89)
- 2
Section
Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)
- 3
Category E16
Other disorders of pancreatic internal secretion
- 4
Code E16.4
Increased secretion of gastrin
Notes for this code
Inclusion terms
- Hypergastrinemia
- Hyperplasia of pancreatic endocrine cells with gastrin excess
- Zollinger-Ellison syndrome
Code first
No “code first” instruction is listed for E16.4.
Use additional code
No “use additional code” instruction is listed for E16.4.
Excludes1
Conditions that should not be reported together with this code.
No Excludes1 note is listed for E16.4.
Excludes2
Conditions not included here that may be reported separately when present.
No Excludes2 note is listed for E16.4.
Source and release
- Data release
- U.S. ICD-10-CM · FY 2027
- Effective date
- Oct 1, 2026
- Publisher
- Vero Scribe Inc.
This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.
Frequently asked questions
What does ICD-10-CM code E16.4 mean?
E16.4 is the FY 2027 U.S. ICD-10-CM code for “Increased secretion of gastrin.”
Is E16.4 a billable or specific ICD-10-CM code?
Yes. In the FY 2027 reference data used on this page, E16.4 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.
Where is E16.4 located in ICD-10-CM?
E16.4 is listed in Chapter 4, Endocrine, nutritional and metabolic diseases (E00-E89), within Other disorders of glucose regulation and pancreatic internal secretion (E15-E16) (E15–E16), under category E16, Other disorders of pancreatic internal secretion.
What coding notes are listed for E16.4?
Its listed inclusion terms are Hypergastrinemia; Hyperplasia of pancreatic endocrine cells with gastrin excess; Zollinger-Ellison syndrome. No code-first instruction is listed. No Excludes1 note is listed. No Excludes2 note is listed.