U.S. ICD-10-CM · FY 2027

D59.31 ICD-10-CM Code: Infection-associated hemolytic-uremic syndrome

A clear reference for the official code description, hierarchy, and related coding information from the FY 2027 U.S. release.

Code definition

Official description

D59.31

Infection-associated hemolytic-uremic syndrome

ICD-10-CM diagnosis code · United States clinical modification

Classification

Where D59.31 sits

  1. 1

    Chapter 3

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

  2. 2

    Section

    Hemolytic anemias (D55-D59)

  3. 3

    Category D59

    Acquired hemolytic anemia

  4. 4

    Subcategory D59.3

    Hemolytic-uremic syndrome

  5. 5

    Code D59.31

    Infection-associated hemolytic-uremic syndrome

Documentation details

Notes for this code

Inclusion terms

  • Shiga toxin-producing E. coli [STEC] related hemolytic uremic syndrome
  • Typical hemolytic uremic syndrome

Code first

No “code first” instruction is listed for D59.31.

Use additional code

  • code to identify associated infection, such as :
  • E. coli infection (B96.2-)
  • Human immunodeficiency virus [HIV] disease (B20)
  • Pneumococcal meningitis (G00.1)
  • Pneumococcal pneumonia (J13)
  • Sepsis due to Streptococcus pneumoniae (A40.3)
  • Shigella dysenteriae (A03.9)
  • Streptococcus pneumoniae as the cause of diseases classified elsewhere (B95.3)

Excludes1

Conditions that should not be reported together with this code.

No Excludes1 note is listed for D59.31.

Excludes2

Conditions not included here that may be reported separately when present.

No Excludes2 note is listed for D59.31.

Transparency

Source and release

Data release

U.S. ICD-10-CM · FY 2027

Effective date

Oct 1, 2026

This reference is generated from Vero’s ICD-10-CM description, hierarchy, and code-note dataset. The visible content and structured data share that source.

Review the CDC/NCHS ICD-10-CM source

Code-specific guidance

Frequently asked questions

What does ICD-10-CM code D59.31 mean?

D59.31 is the FY 2027 U.S. ICD-10-CM code for “Infection-associated hemolytic-uremic syndrome.”

Is D59.31 a billable or specific ICD-10-CM code?

Yes. In the FY 2027 reference data used on this page, D59.31 has no child codes and is presented as a billable/specific code. Always confirm the active code set and payer requirements before use.

Where is D59.31 located in ICD-10-CM?

D59.31 is listed in Chapter 3, Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), within Hemolytic anemias (D55-D59) (D55–D59), under category D59, Acquired hemolytic anemia and subcategory D59.3, Hemolytic-uremic syndrome.

What coding notes are listed for D59.31?

Its listed inclusion terms are Shiga toxin-producing E. coli [STEC] related hemolytic uremic syndrome; Typical hemolytic uremic syndrome. No code-first instruction is listed. Additional-code instructions: code to identify associated infection, such as :; E. coli infection (B96.2-); Human immunodeficiency virus [HIV] disease (B20); Pneumococcal meningitis (G00.1); Pneumococcal pneumonia (J13); Sepsis due to Streptococcus pneumoniae (A40.3); Shigella dysenteriae (A03.9); Streptococcus pneumoniae as the cause of diseases classified elsewhere (B95.3). No Excludes1 note is listed. No Excludes2 note is listed.

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